HitPredict - High confidence protein-protein interactions

Protein: ICOS
Inducible T-cell costimulator (Activation-inducible lymphocyte immunomediatory molecule) (CD28 and CTLA-4-like protein) (CCLP) (CD28-related protein 1) (CRP-1) (CD antigen CD278)

Gene: ICOS
Organism: Mus musculus
Interactions: 6
UniProt ID: Q9WVS0

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0031295 - T cell costimulation

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1440815	ICOSL ICOS ligand	1	1	Small-scale	0.552	High
686989	P85A Phosphatidylinositol 3-kinase regulatory subunit alpha	1	1	Small-scale	0.457	High
1490165	TBK1 Serine/threonine-protein kinase TBK1	1	1	Small-scale	0.407	High
1197149	RC3H1 Roquin-1	2	0	Small-scale	0.313	High
1225448	IRF4 Interferon regulatory factor 4	1	0	Small-scale	0.249	Low
1408720	FOXP3 Forkhead box protein P3	1	0	Small-scale	0.249	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025