Protein: IRF4
Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP)

Gene: IRF4
Organism: Mus musculus
Interactions: 35
UniProt ID: Q64287

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1221274

PRDM1
PR domain zinc finger protein 1

5

1

Small-scale

0.702

High

617833

IL10
Interleukin-10

4

1

Small-scale

0.687

High

604524

SPI1
Transcription factor PU.1

3

10

Small-scale

0.660

High

204599

BATF
Basic leucine zipper transcriptional factor ATF-like

1

2

Small-scale

0.618

High

660991

IRF8
Interferon regulatory factor 8

1

15

Small-scale

0.618

High

459948

IL4
Interleukin-4

2

3

Small-scale

0.584

High

1009389

C2TA
MHC class II transactivator

2

7

Small-scale

0.552

High

237257

TLX3
T-cell leukemia homeobox protein 3

1

5

High-throughput

0.541

High

867603

CCR7
C-C chemokine receptor type 7

2

3

Small-scale

0.533

High

648060

MYD88
Myeloid differentiation primary response protein MyD88

1

20

Small-scale

0.515

High

1225442

FOXP3
Forkhead box protein P3

1

4

Small-scale

0.515

High

266905

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

0

Small-scale

0.512

High

1225443

IL21
Interleukin-21

1

0

Small-scale

0.493

High

147373

HXK2
Hexokinase-2

1

3

Small-scale

0.479

High

681985

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

19

Small-scale

0.479

High

719594

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

3

Small-scale

0.479

High

849295

IL12B
Interleukin-12 subunit beta

1

8

Small-scale

0.479

High

1038082

PAX5
Paired box protein Pax-5

1

1

Small-scale

0.479

High

1221152

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

20

Small-scale

0.479

High

1225445

TLR4
Toll-like receptor 4

1

13

Small-scale

0.479

High

1225446

FOXO1
Forkhead box protein O1

1

7

Small-scale

0.479

High

599245

IL7RA
Interleukin-7 receptor subunit alpha

1

0

Small-scale

0.458

High

1225444

PYGL
Glycogen phosphorylase, liver form

1

0

Small-scale

0.458

High

266923

CATS
Cathepsin S

1

3

Small-scale

0.437

High

378662

IL2RA
Interleukin-2 receptor subunit alpha

1

1

Small-scale

0.437

High

638274

CYTC
Cystatin-C

1

3

Small-scale

0.437

High

837298

CD86
T-lymphocyte activation antigen CD86

1

3

Small-scale

0.437

High

1021267

I12R2
Interleukin-12 receptor subunit beta-2

1

2

Small-scale

0.437

High

1025973

CD80
T-lymphocyte activation antigen CD80

1

3

Small-scale

0.437

High

662686

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

0

Small-scale

0.426

High

582052

IL9
Interleukin-9

1

0

Small-scale

0.249

Low

732016

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

0

Small-scale

0.249

Low

1225441

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

0

Small-scale

0.249

Low

1225447

FAIM1
Fas apoptotic inhibitory molecule 1

1

0

Small-scale

0.249

Low

1225448

ICOS
Inducible T-cell costimulator

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025