HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: MK15 (Q8TD08)
Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)
Gene: MAPK15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005576 - extracellular region
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 544
+	Hs
		882055 TCPG_HUMAN (3-532): 0: 561: 28.33		MK15_HUMAN (1-544): 0: 546: 100.00
+	Hs
		668007 TCPH_HUMAN (4-532): 0: 591: 34.08		CDK2_HUMAN (10-315): 3.61e-141: 411: 38.31
+	Hs
		667763 TCPB_HUMAN (1-535): 0: 586: 100.00		CDK2_HUMAN (10-315): 3.61e-141: 411: 38.31
+	Sc
		574682 TCPB_YEAST (9-532): 0: 566: 65.71		KSS1_YEAST (1-346): 3.6e-138: 406: 41.14
+	Hs
		667642 TCPG_HUMAN (3-532): 0: 561: 28.33		CDK2_HUMAN (10-315): 3.61e-141: 411: 38.31
+	Sc
		574695 TCPH_YEAST (1-532): 0: 559: 33.09		KSS1_YEAST (1-346): 3.6e-138: 406: 41.14
+	Hs
		610532 TCPA_HUMAN (5-533): 0: 541: 34.30		CDK2_HUMAN (10-315): 3.61e-141: 411: 38.31
+	Hs
		667634 TCPE_HUMAN (1-528): 0: 541: 32.29		CDK2_HUMAN (10-315): 3.61e-141: 411: 38.31
+	Rn
		640023 TCPB_RAT (1-535): 0: 584: 97.76		MK03_RAT (12-313): 1.33e-77: 251: 45.25
+	Rn
		640059 TCPG_RAT (3-532): 0: 565: 28.89		MK03_RAT (12-313): 1.33e-77: 251: 45.25
+	Rn
		640047 TCPE_RAT (8-524): 0: 554: 33.02		MK03_RAT (12-313): 1.33e-77: 251: 45.25
+	Rn
		639928 TCPA_RAT (7-532): 4.35e-83: 270: 34.85		MK03_RAT (12-313): 1.33e-77: 251: 45.25