HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: ARP3B (Q9P1U1)
Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4)
Gene: ACTR3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Cpn60_TCP1
Common GO terms	GO:0005524 - ATP binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 418
+	Hs
		958178 TCPH_HUMAN (4-532): 0: 591: 34.08		ARP3_HUMAN (1-418): 0: 571: 90.67
+	Hs
		958082 TCPB_HUMAN (1-535): 0: 586: 100.00		ARP3_HUMAN (1-418): 0: 571: 90.67
+	Hs
		881855 TCPG_HUMAN (3-532): 0: 561: 28.33		ARP3_HUMAN (1-418): 0: 571: 90.67
+	Hs
		1407604 TCPH_HUMAN (4-532): 0: 591: 34.08		ARP3B_HUMAN (1-418): 0: 528: 100.00
+	Hs
		953055 TCPH_HUMAN (4-532): 0: 591: 34.08		ACTB_HUMAN (1-414): 0: 526: 35.42
+	Hs
		993309 TCPH_HUMAN (4-532): 0: 591: 34.08		ACTG_HUMAN (1-414): 0: 526: 35.18
+	Hs
		875892 TCPE_HUMAN (1-528): 0: 541: 32.29		ARP3_HUMAN (1-418): 0: 571: 90.67
+	Hs
		952738 TCPB_HUMAN (1-535): 0: 586: 100.00		ACTB_HUMAN (1-414): 0: 526: 35.42
+	Hs
		993131 TCPB_HUMAN (1-535): 0: 586: 100.00		ACTG_HUMAN (1-414): 0: 526: 35.18
+	Hs
		995790 TCPH_HUMAN (4-532): 0: 591: 34.08		ACTC_HUMAN (3-414): 0: 516: 35.84
+	Hs
		995536 TCPB_HUMAN (1-535): 0: 586: 100.00		ACTC_HUMAN (3-414): 0: 516: 35.84
+	Hs
		996425 TCPB_HUMAN (1-535): 0: 586: 100.00		ACTS_HUMAN (3-414): 0: 516: 35.84
+	Hs
		882200 TCPG_HUMAN (3-532): 0: 561: 28.33		ARP3B_HUMAN (1-418): 0: 528: 100.00
+	Hs
		881853 TCPG_HUMAN (3-532): 0: 561: 28.33		ACTB_HUMAN (1-414): 0: 526: 35.42
+	Hs
		881869 TCPG_HUMAN (3-532): 0: 561: 28.33		ACTG_HUMAN (1-414): 0: 526: 35.18
+	Sc
		810741 TCPB_YEAST (9-532): 0: 566: 65.71		ACT_YEAST (1-414): 0: 520: 34.46
+	Sc
		844424 TCPH_YEAST (1-532): 0: 559: 33.09		ACT_YEAST (1-414): 0: 520: 34.46
+	Hs
		881871 TCPG_HUMAN (3-532): 0: 561: 28.33		ACTC_HUMAN (3-414): 0: 516: 35.84
+	Hs
		875890 TCPE_HUMAN (1-528): 0: 541: 32.29		ACTB_HUMAN (1-414): 0: 526: 35.42
+	Hs
		875902 TCPE_HUMAN (1-528): 0: 541: 32.29		ACTA_HUMAN (3-414): 0: 514: 35.84