HitPredict

Interactor 1: F8VPR5 (F8VPR5)
histone acetyltransferase (EC 2.3.1.48)
Gene: Crebbp

Interactor 2: HDA10 (Q6P3E7)
Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10)
Gene: Hdac10

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2441 Mm			1 666
+	Hs
		1270347 CBP_HUMAN (1-2441): 0: 1094: 94.89		HDAC2_HUMAN (7-457): 6.02e-158: 465: 20.30
+	Hs
		1038592 CBP_HUMAN (1-2441): 0: 1094: 94.89		HDAC1_HUMAN (7-383): 2.29e-157: 464: 21.65
+	Hs
		177346 CBP_HUMAN (1-2441): 0: 1094: 94.89		HDAC3_HUMAN (4-411): 1.77e-143: 426: 18.57
+	Hs
		998937 EP300_HUMAN (1-2426): 0: 887: 54.94		HDAC2_HUMAN (7-457): 6.02e-158: 465: 20.30
+	Hs
		998668 EP300_HUMAN (1-2426): 0: 887: 54.94		HDAC1_HUMAN (7-383): 2.29e-157: 464: 21.65
+	Hs
		177279 EP300_HUMAN (1-2426): 0: 887: 54.94		HDAC3_HUMAN (4-411): 1.77e-143: 426: 18.57
+	Dm
		116005 M9PH39_DROME (514-2358): 0: 785: 36.04		HDAC1_DROME (7-429): 4.92e-156: 462: 18.66
+	Hs
		998913 EP300_HUMAN (1-2426): 0: 887: 54.94		HDAC7_HUMAN (427-666): 1.83e-78: 270: 17.29
+	Hs
		999167 EP300_HUMAN (1-2426): 0: 887: 54.94		HDAC6_HUMAN (386-665): 1.83e-56: 209: 13.89
+	Hs
		1017332 BPTF_HUMAN (1828-2216): 6.52e-12: 74: 14.29		HDAC2_HUMAN (7-457): 6.02e-158: 465: 20.30
+	Hs
		1017292 BPTF_HUMAN (1828-2216): 6.52e-12: 74: 14.29		HDAC1_HUMAN (7-383): 2.29e-157: 464: 21.65
+	Sc
		693060 GCN5_YEAST (1111-1193): 6.22e-12: 72.4: 37.35		RPD3_YEAST (4-400): 2.59e-148: 439: 21.32
+	Mm
		101519 F8VQ93_MOUSE (1046-1206): 1.38e-42: 174: 29.76		HDAC4_MOUSE (358-665): 5.68e-80: 276: 15.01
+	Mm
		1157772 PHIP_MOUSE (1046-1206): 7.09e-42: 172: 29.76		HDAC4_MOUSE (358-665): 5.68e-80: 276: 15.01
+	Hs
		1262831 PHIP_HUMAN (1046-1206): 6.9e-43: 175: 31.74		HDAC6_HUMAN (386-665): 1.83e-56: 209: 13.89
+	Hs
		1354158 TRI33_HUMAN (611-1238): 9.63e-42: 171: 14.95		HDAC6_HUMAN (386-665): 1.83e-56: 209: 13.89
+	Hs
		1260194 BRWD1_HUMAN (1105-1193): 3.01e-11: 71.6: 40.00		HDAC7_HUMAN (427-666): 1.83e-78: 270: 17.29