HitPredict

Interactor 1: H2A (P84051)
Histone H2A
Gene: His2A

Interactor 2: CAF1 (Q24572)
Chromatin assembly factor 1 p55 subunit (CAF-1 p55 subunit) (CAF-1) (Nucleosome-remodeling factor 55 kDa subunit) (NURF-55)
Gene: Caf1-55

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17210640
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CAF1C_H4-bd~Histone, Histone~WD40
Common GO terms	GO:0005634 - nucleus GO:0005700 - polytene chromosome GO:0006325 - chromatin organization GO:0031507 - heterochromatin formation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 124 Dm			1 430
+	Hs
		845317 H2A2A_HUMAN (1-122): 1.76e-61: 185: 89.43		LIS1_HUMAN (3-212): 1.37e-39: 148: 10.64
+	Hs
		591570 H2AX_HUMAN (1-120): 6.87e-62: 187: 90.91		WDR5_HUMAN (271-428): 6.65e-34: 131: 24.68
+	Hs
		418917 H2A1B_HUMAN (1-122): 3.59e-61: 185: 88.62		WDR5_HUMAN (271-428): 6.65e-34: 131: 24.68
+	Hs
		502504 H2A1_HUMAN (1-122): 3.29e-61: 185: 89.43		GRWD1_HUMAN (261-428): 3.6e-28: 117: 21.47
+	Hs
		284923 H2AX_HUMAN (1-120): 6.87e-62: 187: 90.91		TAF5L_HUMAN (14-250): 6.64e-26: 111: 14.40
+	Hs
		1158857 H2A2C_HUMAN (1-122): 1.63e-61: 185: 89.43		RBBP7_HUMAN (276-428): 4.23e-17: 84.9: 21.61
+	Hs
		1066325 H2A2C_HUMAN (1-122): 1.63e-61: 185: 89.43		RBBP4_HUMAN (276-428): 5.88e-17: 84.5: 22.84
+	Hs
		1066351 H2A2A_HUMAN (1-122): 1.76e-61: 185: 89.43		RBBP4_HUMAN (276-428): 5.88e-17: 84.5: 22.84
+	Hs
		502431 H2A1_HUMAN (1-122): 3.29e-61: 185: 89.43		DAW1_HUMAN (315-422): 2.48e-15: 79.5: 14.82