HitPredict

Interactor 1: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras, PDZ~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2485 Hs			1 232
+	Hs
		901140 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		893945 PTN13_HUMAN (1-2485): 0: 1895: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		852454 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		925236 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		892339 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		900421 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		436277 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		915636 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120411 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		1020220 PTN13_HUMAN (1-2485): 0: 1895: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Mm
		250712 E41L2_MOUSE (375-1061): 2.97e-117: 400: 18.08		RAC1_MOUSE (11-200): 6.76e-80: 239: 38.42
+	Hs
		852620 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		505614 EPB41_HUMAN (414-1119): 2.11e-118: 400: 16.97		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		505620 EPB41_HUMAN (414-1119): 2.11e-118: 400: 16.97		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		892594 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		545616 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		120288 EPB41_HUMAN (414-1119): 2.11e-118: 400: 16.97		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		436506 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		120641 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		505683 EPB41_HUMAN (414-1119): 2.11e-118: 400: 16.97		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21