HitPredict

Interactor 1: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2485 Hs			1 530
+	Hs
		369500 PTN13_HUMAN (1-2485): 0: 1895: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		505665 EPB41_HUMAN (414-1119): 2.11e-118: 400: 16.97		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		204716 E41L2_HUMAN (367-1065): 2.11e-113: 389: 17.33		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		719567 MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269674 E41L5_HUMAN (513-1220): 6.79e-115: 385: 16.35		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		719756 RADI_HUMAN (574-969): 6.68e-116: 383: 26.94		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368880 EPB41_HUMAN (414-1119): 2.11e-118: 400: 16.97		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370429 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		204590 E41L2_HUMAN (367-1065): 2.11e-113: 389: 17.33		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370483 E41L5_HUMAN (513-1220): 6.79e-115: 385: 16.35		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369088 RADI_HUMAN (574-969): 6.68e-116: 383: 26.94		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		490000 PTPRF_HUMAN (2189-2468): 4.55e-89: 326: 30.38		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377681 E41L1_HUMAN (471-1098): 1e-116: 395: 18.37		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		204593 E41L2_HUMAN (367-1065): 2.11e-113: 389: 17.33		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377170 PTN9_HUMAN (2136-2470): 4.76e-112: 372: 27.04		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		1069954 PTPRK_HUMAN (2206-2470): 8.98e-55: 214: 23.83		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		573834 PTN1_HUMAN (2229-2465): 2.56e-45: 172: 37.40		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369041 PTN6_HUMAN (2215-2480): 9.54e-47: 181: 40.48		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368948 PTN1_HUMAN (2229-2465): 2.56e-45: 172: 37.40		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487363 PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59