HitPredict

Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: EPHA7 (Q15375)
Ephrin type-A receptor 7 (EC 2.7.10.1) (EPH homology kinase 3) (EHK-3) (EPH-like kinase 11) (EK11) (hEK11)
Gene: EPHA7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1, PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 998
+	Hs
		872639 DLG1_HUMAN (1-904): 0: 725: 100.00		EPHA4_HUMAN (4-998): 0: 1224: 62.29
+	Hs
		872433 DLG1_HUMAN (1-904): 0: 725: 100.00		EPHA5_HUMAN (6-988): 0: 1197: 62.65
+	Hs
		159214 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		1049958 SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		1072518 MPP7_HUMAN (96-459): 7.98e-17: 86.8: 14.80		EPHA7_HUMAN (1-998): 0: 1310: 100.00
+	Hs
		159179 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		EPHA4_HUMAN (4-998): 0: 1224: 62.29
+	Hs
		665600 SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49		EPHB2_HUMAN (32-997): 0: 1178: 57.48
+	Hs
		674412 DLG1_HUMAN (1-904): 0: 725: 100.00		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		665293 DLG5_HUMAN (202-404): 4.58e-19: 95.5: 32.02		EPHA2_HUMAN (29-989): 0: 1080: 50.42
+	Hs
		674422 SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49		UFO_HUMAN (271-950): 5.35e-149: 467: 22.78
+	Hs
		159139 CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64		HCK_HUMAN (611-891): 2.73e-64: 228: 42.40
+	Hs
		412128 DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64		FYN_HUMAN (627-891): 1.29e-62: 224: 43.45