Protein: SMAD2
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2) (SMAD family member 2) (SMAD 2) (Smad2)

Gene: SMAD2
Organism: Mus musculus
Interactions: 35
UniProt ID: Q62432

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001657 - ureteric bud development
GO:0001701 - in utero embryonic development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021506

SMAD4
Mothers against decapentaplegic homolog 4

6

18

Small-scale

0.935

High

312717

FOXH1
Forkhead box protein H1

2

18

Small-scale

0.586

High

1224193

ITCH
E3 ubiquitin-protein ligase Itchy

1

20

Small-scale

0.536

High

697746

LEF1
Lymphoid enhancer-binding factor 1

1

20

Small-scale

0.515

High

999939

HXD13
Homeobox protein Hox-D13

1

18

Small-scale

0.508

High

1224172

HXA13
Homeobox protein Hox-A13

1

19

Small-scale

0.508

High

900711

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

17

Small-scale

0.501

High

1224189

ERBIN
Erbin

1

10

Small-scale

0.501

High

1224191

ZNF8
Zinc finger protein 8

1

4

Small-scale

0.501

High

1224195

RN111
E3 ubiquitin-protein ligase Arkadia

1

9

Small-scale

0.501

High

1224199

ZEB2
Zinc finger E-box-binding homeobox 2

1

14

High-throughput

0.481

High

59146

PRD16
Histone-lysine N-methyltransferase PRDM16

1

13

Small-scale

0.479

High

267137

PKNX1
Homeobox protein PKNOX1

1

11

Small-scale

0.479

High

465919

CO3A1

1

16

Small-scale

0.479

High

486822

CADH1
Cadherin-1

1

4

Small-scale

0.479

High

518516

MYOD1
Myoblast determination protein 1

1

4

Small-scale

0.479

High

536207

CO1A1
Collagen alpha-1(I) chain

1

16

Small-scale

0.479

High

835790

PBX1
Pre-B-cell leukemia transcription factor 1

1

9

Small-scale

0.479

High

862603

YAP1
Transcriptional coactivator YAP1

1

20

Small-scale

0.479

High

1063097

GATA4
Transcription factor GATA-4

1

8

Small-scale

0.479

High

1190303

SF3B2
Splicing factor 3B subunit 2

1

5

Small-scale

0.479

High

1190550

Q3UM65
Runt-related transcription factor

1

16

Small-scale

0.479

High

1221360

FSHB
Follitropin subunit beta

1

2

Small-scale

0.479

High

1221964

MEF2A
Myocyte-specific enhancer factor 2A

1

2

Small-scale

0.479

High

1223471

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

8

Small-scale

0.479

High

1224188

OTUB1
Ubiquitin thioesterase OTUB1

1

5

Small-scale

0.479

High

1224192

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

10

Small-scale

0.479

High

1224196

ZMYM2
Zinc finger MYM-type protein 2

1

5

Small-scale

0.479

High

1224197

WWTR1
WW domain-containing transcription regulator protein 1

1

20

Small-scale

0.479

High

1224198

4ET
Eukaryotic translation initiation factor 4E transporter

1

4

Small-scale

0.479

High

1224190

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.458

High

148070

PAR3
Proteinase-activated receptor 3

1

3

Small-scale

0.457

High

915617

HMGA2
High mobility group protein HMGI-C

1

3

High-throughput

0.445

High

312009

CO5A1

1

16

Small-scale

0.437

High

1224194

PEX6
Peroxisomal ATPase PEX6

1

5

Small-scale

0.437

High


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Last updated: 11Aug2025