HitPredict

Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	19826003, 17827148, 22990118
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 2089
+	Hs
		174891 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		MDC1_HUMAN (1-2089): 0: 665: 100.00
+	Hs
		1057017 APC7_HUMAN (75-607): 2.88e-19: 93.7: 12.73		MDC1_HUMAN (1-2089): 0: 665: 100.00
+	Hs
		1057016 CDC23_HUMAN (9-383): 2.3e-15: 81.4: 9.71		MDC1_HUMAN (1-2089): 0: 665: 100.00
+	Hs
		672833 CDC27_HUMAN (4-194): 3.68e-15: 81: 17.80		MDC1_HUMAN (1-2089): 0: 665: 100.00
+	Hs
		1018938 CDC16_HUMAN (1-620): 1.68e-124: 382: 100.00		TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87
+	Hs
		1022924 CDC16_HUMAN (1-620): 1.68e-124: 382: 100.00		PAXI1_HUMAN (1840-2081): 6.55e-55: 212: 27.56
+	Hs
		174836 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87
+	Hs
		1019165 APC7_HUMAN (75-607): 2.88e-19: 93.7: 12.73		TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87
+	Hs
		174698 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53
+	Hs
		1019164 CDC23_HUMAN (9-383): 2.3e-15: 81.4: 9.71		TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87
+	Hs
		672821 CDC27_HUMAN (4-194): 3.68e-15: 81: 17.80		TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87
+	Hs
		801454 CDC23_HUMAN (9-383): 2.3e-15: 81.4: 9.71		KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53
+	Hs
		1173268 APC7_HUMAN (75-607): 2.88e-19: 93.7: 12.73		PAXI1_HUMAN (1840-2081): 6.55e-55: 212: 27.56
+	Hs
		1173267 CDC23_HUMAN (9-383): 2.3e-15: 81.4: 9.71		PAXI1_HUMAN (1840-2081): 6.55e-55: 212: 27.56
+	Hs
		672854 CDC27_HUMAN (4-194): 3.68e-15: 81: 17.80		PAXI1_HUMAN (1840-2081): 6.55e-55: 212: 27.56
+	Hs
		311815 CTR9_HUMAN (96-617): 5.62e-29: 125: 10.36		TACC2_HUMAN (151-1928): 1.23e-24: 115: 9.64
+	Hs
		92366 CTR9_HUMAN (96-617): 5.62e-29: 125: 10.36		E9PBC6_HUMAN (102-1944): 1.44e-22: 108: 7.80