Protein: ANR46
Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S)

Gene: ANR46, ANKRD46
Organism: Homo sapiens
Interactions: 130
UniProt ID: Q86W74

Gene Ontology (top 5):
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1144625

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

5

High-throughput

0.839

High

580797

PVR
Poliovirus receptor

2

10

High-throughput

0.783

High

1292103

AMGO1
Amphoterin-induced protein 1

2

5

High-throughput

0.783

High

1292149

SCN3B
Sodium channel regulatory subunit beta-3

2

6

High-throughput

0.783

High

543429

PSG1
Pregnancy-specific beta-1-glycoprotein 1

3

16

High-throughput

0.770

High

1158734

PSG3
Pregnancy-specific beta-1-glycoprotein 3

3

11

High-throughput

0.770

High

1292153

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

11

High-throughput

0.726

High

1004111

CXAR
Coxsackievirus and adenovirus receptor

2

6

High-throughput

0.700

High

1187480

AR13B
ADP-ribosylation factor-like protein 13B

2

6

High-throughput

0.700

High

244478

MGRN1
E3 ubiquitin-protein ligase MGRN1

4

1

High-throughput

0.697

High

520905

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

4

High-throughput

0.691

High

607384

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

4

High-throughput

0.691

High

586186

CD1E
T-cell surface glycoprotein CD1e, membrane-associated

1

5

High-throughput

0.618

High

1292105

SACA3
Sperm acrosome membrane-associated protein 3

1

1

High-throughput

0.618

High

1292139

SIRPD
Signal-regulatory protein delta

1

2

High-throughput

0.618

High

1292150

BTNL2
Butyrophilin-like protein 2

1

11

High-throughput

0.618

High

1292151

FBX2
F-box only protein 2

1

4

High-throughput

0.618

High

1292112

RN149
E3 ubiquitin-protein ligase RNF149

2

8

High-throughput

0.611

High

629549

CD22
B-cell receptor CD22

2

12

High-throughput

0.606

High

850836

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

6

High-throughput

0.606

High

1087170

STX4
Syntaxin-4

2

19

High-throughput

0.606

High

1213640

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

2

3

High-throughput

0.606

High

1292106

LRC25
Leucine-rich repeat-containing protein 25

2

1

High-throughput

0.606

High

1292107

EMC5
ER membrane protein complex subunit 5

2

1

High-throughput

0.606

High

1292120

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

2

3

High-throughput

0.606

High

1292123

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

10

High-throughput

0.606

High

1292148

TM248
Transmembrane protein 248

2

1

High-throughput

0.606

High

296365

ATRN
Attractin

3

13

High-throughput

0.604

High

1281691

MEGF8
Multiple epidermal growth factor-like domains protein 8

2

13

High-throughput

0.601

High

883425

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

0

High-throughput

0.580

High

1219806

PLPP4
Phospholipid phosphatase 4

2

0

High-throughput

0.580

High

1233752

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.580

High

1248413

CP054
Transmembrane protein C16orf54

2

0

High-throughput

0.580

High

1292104

INLR1
Interferon lambda receptor 1

2

0

High-throughput

0.580

High

1292113

F174A
Membrane protein FAM174A

2

0

High-throughput

0.580

High

1292116

SCTM1
Secreted and transmembrane protein 1

2

0

High-throughput

0.580

High

1292124

APH1A
Gamma-secretase subunit APH-1A

2

0

High-throughput

0.580

High

1292154

NSG2
Neuronal vesicle trafficking-associated protein 2

2

0

High-throughput

0.580

High

188925

TMPS2
Transmembrane protease serine 2

2

4

High-throughput

0.553

High

337890

CLD7
Claudin-7

2

1

High-throughput

0.553

High

584685

MCP
Membrane cofactor protein

2

1

High-throughput

0.553

High

590303

MUC1
Mucin-1

2

13

High-throughput

0.553

High

746212

STX2
Syntaxin-2

2

19

High-throughput

0.553

High

914441

EFNB2
Ephrin-B2

2

3

High-throughput

0.553

High

926800

VMAT1
Chromaffin granule amine transporter

2

3

High-throughput

0.553

High

942423

CLD20
Claudin-20

2

1

High-throughput

0.553

High

1022899

EFNB1
Ephrin-B1

2

3

High-throughput

0.553

High

1159592

STX1A
Syntaxin-1A

2

19

High-throughput

0.553

High

1279325

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

3

High-throughput

0.553

High

1292108

KASH5
Protein KASH5

2

10

High-throughput

0.553

High

1292110

DHB11
Estradiol 17-beta-dehydrogenase 11

2

3

High-throughput

0.553

High

1292114

GP152
Probable G-protein coupled receptor 152

2

13

High-throughput

0.553

High

1292118

THAP4
Peroxynitrite isomerase THAP4

2

3

High-throughput

0.553

High

1292136

ELOV4
Very long chain fatty acid elongase 4

2

1

High-throughput

0.553

High

1292146

S39A9
Zinc transporter ZIP9

2

4

High-throughput

0.553

High

827217

ARL1
ADP-ribosylation factor-like protein 1

1

2

High-throughput

0.553

High

901364

RAB7A
Ras-related protein Rab-7a

1

14

High-throughput

0.553

High

181358

PGRC2
Membrane-associated progesterone receptor component 2

1

1

High-throughput

0.536

High

698837

CALX
Calnexin

1

5

High-throughput

0.536

High

1030185

IL5RA
Interleukin-5 receptor subunit alpha

1

9

High-throughput

0.536

High

1084017

SIA4A
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

1

3

High-throughput

0.536

High

1218528

ATRN1
Attractin-like protein 1

1

11

High-throughput

0.536

High

1292135

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

5

High-throughput

0.536

High

1292138

LMA2L
VIP36-like protein

1

1

High-throughput

0.536

High

1292155

SRPRB
Signal recognition particle receptor subunit beta

1

4

High-throughput

0.536

High

60366

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.513

High

295843

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.513

High

1292131

SEC62
Translocation protein SEC62

1

0

High-throughput

0.513

High

426111

PPB1
Alkaline phosphatase, placental type

1

1

High-throughput

0.489

High

570690

EDN3
Endothelin-3

1

1

High-throughput

0.489

High

643187

BMP5
Bone morphogenetic protein 5

1

2

High-throughput

0.489

High

945895

INHBE
Inhibin beta E chain

1

2

High-throughput

0.489

High

1101278

SLAF1
Signaling lymphocytic activation molecule

1

17

High-throughput

0.489

High

1116235

PTC1
Protein patched homolog 1

1

1

High-throughput

0.489

High

1292119

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

3

High-throughput

0.489

High

1292125

FAF2
FAS-associated factor 2

1

4

High-throughput

0.489

High

1292128

RN157
E3 ubiquitin ligase RNF157

1

1

High-throughput

0.489

High

1292129

TSN18
Tetraspanin-18

1

2

High-throughput

0.489

High

1292132

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

1

High-throughput

0.489

High

1292140

TMX1
Thioredoxin-related transmembrane protein 1

1

9

High-throughput

0.489

High

1292143

ITM2C
Integral membrane protein 2C

1

3

High-throughput

0.489

High

1292152

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

5

High-throughput

0.489

High

1292157

ST14
Suppressor of tumorigenicity 14 protein

1

3

High-throughput

0.489

High

1292158

AP1M2
AP-1 complex subunit mu-2

1

1

High-throughput

0.489

High

1207710

TMM31
Transmembrane protein 31

1

1

High-throughput

0.481

High

117006

J3KQ12
Seipin

1

2

High-throughput

0.470

High

193424

GPR42
G-protein coupled receptor 42

1

9

High-throughput

0.470

High

1292115

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.460

High

537453

HSP7C
Heat shock cognate 71 kDa protein

1

17

High-throughput

0.445

High

1238344

RETST
All-trans-retinol 13,14-reductase

1

8

High-throughput

0.445

High

1292144

VPS45
Vacuolar protein sorting-associated protein 45

1

4

High-throughput

0.445

High

194714

FFAR2
Free fatty acid receptor 2

1

9

High-throughput

0.439

High

779711

MOT8
Monocarboxylate transporter 8

1

9

High-throughput

0.439

High

1292126

BSCL2
Seipin

1

2

High-throughput

0.439

High

1160408

TAZ
Tafazzin

3

0

High-throughput

0.347

High

1292130

GPHA2
Glycoprotein hormone alpha-2

3

0

High-throughput

0.347

High

1231719

PVRIG
Transmembrane protein PVRIG

2

0

High-throughput

0.328

High

1292156

INSL5
Insulin-like peptide INSL5

2

0

High-throughput

0.328

High

49528

SHSA3
Protein shisa-3 homolog

2

0

High-throughput

0.316

High

1102409

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.316

High

1108947

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1142867

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

1185985

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.316

High

1207537

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1291412

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.316

High

1292109

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.316

High

1292111

RELL2
RELT-like protein 2

2

0

High-throughput

0.316

High

1292117

CLC4D
C-type lectin domain family 4 member D

2

0

High-throughput

0.316

High

1292122

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.316

High

1292127

SUSD3
Sushi domain-containing protein 3

2

0

High-throughput

0.316

High

1292133

TMM79
Transmembrane protein 79

2

0

High-throughput

0.316

High

1292134

CRUM3
Protein crumbs homolog 3

2

0

High-throughput

0.316

High

1292137

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

1292142

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.316

High

219195

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.282

High

252531

SEP15
Selenoprotein F

1

0

High-throughput

0.279

Low

377129

TSHB
Thyrotropin subunit beta

1

0

High-throughput

0.279

Low

880033

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.279

Low

946358

FAM3B
Protein FAM3B

1

0

High-throughput

0.279

Low

956079

SPCS3
Signal peptidase complex subunit 3

1

0

High-throughput

0.279

Low

1025930

NDP
Norrin

1

0

High-throughput

0.279

Low

1091942

SEC20
Vesicle transport protein SEC20

1

0

High-throughput

0.279

Low

1143733

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.279

Low

1197247

MBRL
Membralin

1

0

High-throughput

0.279

Low

1292121

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low

1292141

VEZA
Vezatin

1

0

High-throughput

0.279

Low

1292145

CBLN4
Cerebellin-4

1

0

High-throughput

0.279

Low

1220000

CST9
Cystatin-9

1

0

High-throughput

0.249

Low

1292147

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

222298

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025