HitPredict

Interactor 1: CDC16 (Q13042)
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Gene: CDC16

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29509190, 21182203
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 530
+	Hs
		369508 CDC16_HUMAN (1-620): 1.68e-124: 382: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1160955 CTR9_HUMAN (96-617): 5.62e-29: 125: 10.36		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		175077 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269882 APC7_HUMAN (75-607): 2.88e-19: 93.7: 12.73		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269881 CDC23_HUMAN (9-383): 2.3e-15: 81.4: 9.71		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		672868 CDC27_HUMAN (4-194): 3.68e-15: 81: 17.80		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369839 CTR9_HUMAN (96-617): 5.62e-29: 125: 10.36		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		174531 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370667 APC7_HUMAN (75-607): 2.88e-19: 93.7: 12.73		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369057 CDC27_HUMAN (4-194): 3.68e-15: 81: 17.80		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		1142644 CTR9_MOUSE (96-617): 1.21e-28: 124: 10.36		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Mm
		1142687 OGT1_MOUSE (371-616): 2.82e-26: 116: 16.67		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		377572 TTC28_HUMAN (269-611): 9.74e-25: 112: 13.89		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Mm
		56867 CDC27_MOUSE (4-194): 2.45e-15: 81.7: 17.28		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		377420 TMTC3_HUMAN (2-201): 8.27e-11: 67.1: 11.98		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487530 CTR9_HUMAN (96-617): 5.62e-29: 125: 10.36		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		174572 OGT1_HUMAN (371-616): 3.19e-26: 116: 16.67		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487163 CDC27_HUMAN (4-194): 3.68e-15: 81: 17.80		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59