Protein: EFNA3
Ephrin-A3 (EFL-2) (EHK1 ligand) (EHK1-L) (EPH-related receptor tyrosine kinase ligand 3) (LERK-3)

Gene: EFNA3
Organism: Homo sapiens
Interactions: 106
UniProt ID: P52797

Gene Ontology (top 5):
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005886 - plasma membrane
GO:0007267 - cell-cell signaling
GO:0007411 - axon guidance
GO:0016525 - negative regulation of angiogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

710608

EPHA3
Ephrin type-A receptor 3

1

20

Small-scale

0.647

High

635247

EFNA1
Ephrin-A1

1

5

High-throughput

0.618

High

710133

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

914178

EFNA3
Ephrin-A3

1

5

High-throughput

0.618

High

914198

EPHA7
Ephrin type-A receptor 7

1

20

Small-scale

0.618

High

914193

KRA11
Keratin-associated protein 1-1

2

7

High-throughput

0.553

High

914205

NT2NA
Notch homolog 2 N-terminal-like protein A

1

6

High-throughput

0.523

High

474566

VIME
Vimentin

1

20

High-throughput

0.479

High

534817

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

572395

SUIS
Sucrase-isomaltase, intestinal [Cleaved into: Sucrase

1

1

High-throughput

0.479

High

582560

PPAP
Prostatic acid phosphatase

1

3

High-throughput

0.479

High

587593

DESP
Desmoplakin

1

5

High-throughput

0.479

High

658049

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

680286

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

683589

ITA3
Integrin alpha-3

1

3

High-throughput

0.479

High

914180

ACTB
Actin, cytoplasmic 1

1

4

High-throughput

0.479

High

914187

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.479

High

914190

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

914194

SOS1
Son of sevenless homolog 1

1

1

High-throughput

0.479

High

914197

TBB3
Tubulin beta-3 chain

1

15

High-throughput

0.479

High

914204

TBA1A
Tubulin alpha-1A chain

1

12

High-throughput

0.479

High

914225

PCDG6
Protocadherin gamma-A6

1

9

High-throughput

0.479

High

144086

WNT7A
Protein Wnt-7a

1

0

High-throughput

0.458

High

391008

TRFL
Lactotransferrin

1

0

High-throughput

0.458

High

408757

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

456665

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

728125

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.458

High

914206

ABCAD
ATP-binding cassette sub-family A member 13

1

0

High-throughput

0.458

High

914207

TPRA1
Transmembrane protein adipocyte-associated 1

1

0

High-throughput

0.458

High

914216

NLRC4
NLR family CARD domain-containing protein 4

1

0

High-throughput

0.458

High

914179

KR103
Keratin-associated protein 10-3

1

7

High-throughput

0.439

High

255776

USO1
General vesicular transport factor p115

1

4

High-throughput

0.437

High

385071

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.437

High

385251

K2C6A
Keratin, type II cytoskeletal 6A

1

20

High-throughput

0.437

High

389993

ALBU
Albumin

1

2

High-throughput

0.437

High

407264

K2C6B
Keratin, type II cytoskeletal 6B

1

20

High-throughput

0.437

High

407416

K2C1
Keratin, type II cytoskeletal 1

1

19

High-throughput

0.437

High

452209

PDIA1
Protein disulfide-isomerase

1

4

High-throughput

0.437

High

457324

TBB5
Tubulin beta chain

1

15

High-throughput

0.437

High

457956

TRY1
Serine protease 1

1

2

High-throughput

0.437

High

476285

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.437

High

550191

PABP1
Polyadenylate-binding protein 1

1

2

High-throughput

0.437

High

551845

CO6A2

1

1

High-throughput

0.437

High

566119

K1C10
Keratin, type I cytoskeletal 10

1

20

High-throughput

0.437

High

566347

K2C5
Keratin, type II cytoskeletal 5

1

20

High-throughput

0.437

High

570388

GFAP
Glial fibrillary acidic protein

1

20

High-throughput

0.437

High

573397

ENPL
Endoplasmin

1

2

High-throughput

0.437

High

584955

GNS
N-acetylglucosamine-6-sulfatase

1

2

High-throughput

0.437

High

610585

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.437

High

694997

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

697814

CALR
Calreticulin

1

2

High-throughput

0.437

High

698510

CALX
Calnexin

1

2

High-throughput

0.437

High

702177

LYOX
Protein-lysine 6-oxidase

1

4

High-throughput

0.437

High

716796

RL12
Large ribosomal subunit protein uL11

1

2

High-throughput

0.437

High

717413

PDIA3
Protein disulfide-isomerase A3

1

4

High-throughput

0.437

High

720871

KPYR
Pyruvate kinase PKLR

1

1

High-throughput

0.437

High

727736

DNJA1
DnaJ homolog subfamily A member 1

1

2

High-throughput

0.437

High

729196

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

3

High-throughput

0.437

High

771971

K1C9
Keratin, type I cytoskeletal 9

1

20

High-throughput

0.437

High

777429

K22E
Keratin, type II cytoskeletal 2 epidermal

1

20

High-throughput

0.437

High

876454

K2C6C
Keratin, type II cytoskeletal 6C

1

19

High-throughput

0.437

High

881840

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.437

High

898961

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.437

High

914182

LYSC
Lysozyme C

1

1

High-throughput

0.437

High

914184

RL23
Large ribosomal subunit protein uL14

1

2

High-throughput

0.437

High

914185

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.437

High

914186

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.437

High

914188

TBA1B
Tubulin alpha-1B chain

1

12

High-throughput

0.437

High

914189

TBB4B
Tubulin beta-4B chain

1

15

High-throughput

0.437

High

914192

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

6

High-throughput

0.437

High

914195

LG3BP
Galectin-3-binding protein

1

4

High-throughput

0.437

High

914199

K2C71
Keratin, type II cytoskeletal 71

1

20

High-throughput

0.437

High

914200

PAP1L
Polyadenylate-binding protein 1-like

1

2

High-throughput

0.437

High

914203

POTEE
POTE ankyrin domain family member E

1

4

High-throughput

0.437

High

914208

HORN
Hornerin

1

2

High-throughput

0.437

High

914209

DJC10
DnaJ homolog subfamily C member 10

1

6

High-throughput

0.437

High

914211

ZN669
Zinc finger protein 669

1

1

High-throughput

0.437

High

914212

ARHGH
Rho guanine nucleotide exchange factor 17

1

2

High-throughput

0.437

High

914213

ZN300
Zinc finger protein 300

1

1

High-throughput

0.437

High

914214

TBB2B
Tubulin beta-2B chain

1

15

High-throughput

0.437

High

914215

STK33
Serine/threonine-protein kinase 33

1

1

High-throughput

0.437

High

914218

KCTD5
BTB/POZ domain-containing protein KCTD5

1

2

High-throughput

0.437

High

914219

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

1

High-throughput

0.437

High

914220

RTEL1
Regulator of telomere elongation helicase 1

1

2

High-throughput

0.437

High

914221

DJB11
DnaJ homolog subfamily B member 11

1

2

High-throughput

0.437

High

914222

RSP14
Radial spoke head 14 homolog

1

1

High-throughput

0.437

High

914224

LOXL2
Lysyl oxidase homolog 2

1

8

High-throughput

0.437

High

914201

LCE2C
Late cornified envelope protein 2C

2

0

High-throughput

0.316

High

893767

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

326246

PRS23
Serine protease 23

1

0

High-throughput

0.282

High

61824

LAMB4
Laminin subunit beta-4

1

0

High-throughput

0.249

Low

162513

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.249

Low

378675

IGJ
Immunoglobulin J chain

1

0

High-throughput

0.249

Low

588271

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

612566

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.249

Low

723912

LCN1
Lipocalin-1

1

0

High-throughput

0.249

Low

913446

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.249

Low

914181

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.249

Low

914183

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

914191

CP27A
Sterol 26-hydroxylase, mitochondrial

1

0

High-throughput

0.249

Low

914196

ACACA
Acetyl-CoA carboxylase 1

1

0

High-throughput

0.249

Low

914202

Z518A
Zinc finger protein 518A

1

0

High-throughput

0.249

Low

914210

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

1

0

High-throughput

0.249

Low

914217

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

0

High-throughput

0.249

Low

914223

TR112
Multifunctional methyltransferase subunit TRM112-like protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025