HitPredict

Interactor 1: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	31857374, 35271311, 20562859
Identification Methods	affinity chromatography technology, enzymatic study, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 487 Hs			1 125
+	Hs
		1023110 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891118 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306146 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1023104 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1023108 STK4_HUMAN (1-487): 7.89e-170: 489: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1027423 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1027430 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891124 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306153 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1027422 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00
+	Hs
		1027427 STK3_HUMAN (1-487): 2.36e-147: 432: 72.47		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		568789 KAPCA_HUMAN (14-319): 7.68e-123: 364: 26.90		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		891114 M4K2_HUMAN (17-316): 3.72e-75: 254: 42.67		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306141 M4K2_HUMAN (17-316): 3.72e-75: 254: 42.67		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1018189 M4K2_HUMAN (17-316): 3.72e-75: 254: 42.67		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46