HitPredict

Interactor 1: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Interactor 2: TNR27 (Q9HAV5)
Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor)
Gene: EDA2R

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 297
+	Hs
		1020937 TRAF2_HUMAN (3-415): 4e-124: 370: 38.01		TNR27_HUMAN (1-297): 2.52e-171: 477: 100.00
+	Mm
		936250 TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51		TNR27_MOUSE (1-296): 1.61e-173: 483: 80.41
+	Hs
		1334961 TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98		TNR27_HUMAN (1-297): 2.52e-171: 477: 100.00
+	Hs
		1023815 TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00		TNR19_HUMAN (2-199): 3.06e-95: 289: 43.43
+	Hs
		1020953 TRAF2_HUMAN (3-415): 4e-124: 370: 38.01		TNR19_HUMAN (2-199): 3.06e-95: 289: 43.43
+	Hs
		1023749 TRAF1_HUMAN (1-416): 4.57e-172: 489: 100.00		TR19L_HUMAN (20-111): 4.38e-36: 135: 30.44
+	Mm
		936283 TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51		TNR19_MOUSE (2-199): 2.49e-97: 294: 41.92
+	Hs
		1024763 TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77		TNR27_HUMAN (1-297): 2.52e-171: 477: 100.00
+	Hs
		129599 TRAF5_HUMAN (14-261): 1.36e-16: 83.8: 13.91		TNR19_HUMAN (2-199): 3.06e-95: 289: 43.43
+	Hs
		1024787 TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77		EDAR_HUMAN (2-137): 4.35e-53: 181: 30.00