HitPredict

Interactor 1: 2ABA (P63151)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (B55) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha)
Gene: PPP2R2A

Interactor 2: 2ABD (Q66LE6)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta)
Gene: PPP2R2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	28514442, 28330616, 33961781, 31839598, 19156129
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000159 - protein phosphatase type 2A complex GO:0005829 - cytosol GO:0019888 - protein phosphatase regulator activity GO:0051983 - regulation of chromosome segregation GO:0140767 - enzyme-substrate adaptor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 447 Hs			1 453
+	Xl
		1235153 2ABD_XENLA (1-447): 0: 848: 89.04		Q6IRD3_XENLA (1-453): 0: 827: 84.99
+	Hs
		991010 2ABA_HUMAN (1-447): 0: 852: 100.00		2ABB_HUMAN (32-453): 0: 801: 88.15
+	Hs
		991129 2ABA_HUMAN (1-447): 0: 852: 100.00		2ABG_HUMAN (31-453): 0: 787: 85.11
+	Xl
		51214 Q6IRD3_XENLA (1-447): 0: 837: 93.96		2ABB_XENLA (32-453): 0: 794: 87.92
+	Hs
		1023803 2ABD_HUMAN (8-447): 0: 829: 88.86		2ABB_HUMAN (32-453): 0: 801: 88.15
+	Hs
		1226758 2ABD_HUMAN (8-447): 0: 829: 88.86		2ABG_HUMAN (31-453): 0: 787: 85.11
+	Hs
		1023917 2ABB_HUMAN (26-447): 0: 798: 89.10		2ABG_HUMAN (31-453): 0: 787: 85.11