HitPredict

Interactor 1: CSN1 (Q13098)
COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) (Protein MFH)
Gene: GPS1

Interactor 2: BTBD1 (Q9H0C5)
BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)
Gene: BTBD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 491 Hs			1 482
+	Hs
		1024212 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		BTBD2_HUMAN (41-482): 2.73e-131: 392: 82.17
+	Hs
		1024168 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		KLH12_HUMAN (49-481): 1.12e-119: 363: 17.44
+	Hs
		1024173 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		KLH24_HUMAN (26-480): 7.21e-111: 342: 15.89
+	Hs
		1024172 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		KLH10_HUMAN (57-299): 8.67e-77: 253: 21.55
+	Hs
		897308 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		BTBD1_HUMAN (1-482): 3.34e-135: 400: 100.00
+	Hs
		897304 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		BTBD2_HUMAN (41-482): 2.73e-131: 392: 82.17
+	Hs
		897257 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		KLH12_HUMAN (49-481): 1.12e-119: 363: 17.44
+	Hs
		897264 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		KLH24_HUMAN (26-480): 7.21e-111: 342: 15.89
+	Hs
		1024231 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		KLHL8_HUMAN (317-471): 2.67e-17: 86.8: 11.77
+	Hs
		299514 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		KLH18_HUMAN (327-478): 8.46e-14: 75.6: 11.84
+	Hs
		1024232 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		KLHL9_HUMAN (335-458): 1.84e-11: 68.3: 7.26
+	Hs
		1024234 CSN1_HUMAN (1-491): 9.03e-163: 471: 100.00		KLH13_HUMAN (335-458): 2e-11: 68.3: 7.26
+	Hs
		897262 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		KLH10_HUMAN (57-299): 8.67e-77: 253: 21.55
+	Hs
		897321 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		KLHL8_HUMAN (317-471): 2.67e-17: 86.8: 11.77
+	Hs
		299512 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		KLH18_HUMAN (327-478): 8.46e-14: 75.6: 11.84
+	Hs
		897322 CSN2_HUMAN (72-458): 4.14e-76: 247: 14.07		KLH13_HUMAN (335-458): 2e-11: 68.3: 7.26