Protein: CHIO
Beta-chimaerin (Beta-chimerin) (Rho GTPase-activating protein 3)

Gene: CHIO, CHN2
Organism: Homo sapiens
Interactions: 27
UniProt ID: P52757

Gene Ontology (top 5):
GO:0001675 - acrosome assembly
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

914009

RAC1
Ras-related C3 botulinum toxin substrate 1

3

20

Small-scale

0.879

High

593948

NCK1
SH2/SH3 adapter protein NCK1

4

20

High-throughput

0.879

High

222040

NCK2
Cytoplasmic protein NCK2

2

20

High-throughput

0.783

High

586977

CHIN
N-chimaerin

2

12

High-throughput

0.776

High

914015

ANKK1
Ankyrin repeat and protein kinase domain-containing protein 1

2

3

High-throughput

0.700

High

641537

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

91554

C9J3G1
N-chimaerin

1

13

High-throughput

0.618

High

914020

SENP8
Sentrin-specific protease 8

2

1

High-throughput

0.606

High

914022

PRPK
EKC/KEOPS complex subunit TP53RK

2

5

High-throughput

0.576

High

914018

RADIL
Ras-associating and dilute domain-containing protein

2

13

High-throughput

0.571

High

914021

ALS2
Alsin

2

8

High-throughput

0.571

High

914012

SHF
SH2 domain-containing adapter protein F

1

20

High-throughput

0.555

High

442645

RB
Retinoblastoma-associated protein

2

0

High-throughput

0.551

High

856600

BAG6
Large proline-rich protein BAG6

1

5

High-throughput

0.541

High

914023

RANB3
Ran-binding protein 3

2

1

High-throughput

0.526

High

914011

ZYX
Zyxin

1

5

High-throughput

0.479

High

914016

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

1

High-throughput

0.479

High

914019

ELMO2
Engulfment and cell motility protein 2

1

1

High-throughput

0.479

High

914024

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

1

High-throughput

0.479

High

833492

PTGDS
Prostaglandin-H2 D-isomerase

1

1

High-throughput

0.470

High

914014

Q8N9I8
SHF protein

1

1

High-throughput

0.470

High

687167

HMGB2
High mobility group protein B2

1

9

High-throughput

0.437

High

914010

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

8

High-throughput

0.437

High

914013

MGAP
MAX gene-associated protein

1

1

High-throughput

0.437

High

914017

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.300

High

914025

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.249

Low

914008

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025