Protein: RHG23
Rho GTPase-activating protein 23 (Rho-type GTPase-activating protein 23)

Gene: RHG23, ARHGAP23
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q9P227

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0051056 - regulation of small GTPase mediated signal transduction
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

962583

RHOA
Transforming protein RhoA

1

20

High-throughput

0.647

High

988783

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.647

High

730308

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.643

High

1210577

SAPC1
Suppressor APC domain-containing protein 1

3

1

High-throughput

0.609

High

966963

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

189292

IPO8
Importin-8

2

5

High-throughput

0.571

High

451289

NFL
Neurofilament light polypeptide

2

11

High-throughput

0.571

High

581594

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

2

5

High-throughput

0.571

High

691497

1433T
14-3-3 protein theta

2

20

Small-scale

0.571

High

764456

CTNA1
Catenin alpha-1

2

6

High-throughput

0.571

High

1024219

TFAM
Transcription factor A, mitochondrial

2

4

High-throughput

0.571

High

1454232

PNMA2
Paraneoplastic antigen Ma2

2

6

High-throughput

0.549

High

671869

ZA2G
Zinc-alpha-2-glycoprotein

2

0

High-throughput

0.547

High

892279

5NTC
Cytosolic purine 5'-nucleotidase

2

0

High-throughput

0.547

High

1336318

LS14A
Protein LSM14 homolog A

2

0

High-throughput

0.547

High

909217

NEK4
Serine/threonine-protein kinase Nek4

1

5

High-throughput

0.536

High

222540

PLRG1
Pleiotropic regulator 1

2

3

High-throughput

0.521

High

471939

RU2B
U2 small nuclear ribonucleoprotein B''

2

5

High-throughput

0.521

High

478238

SNRPA
U1 small nuclear ribonucleoprotein A

2

3

High-throughput

0.521

High

522521

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

2

3

High-throughput

0.521

High

1157261

AINX
Alpha-internexin

2

10

High-throughput

0.521

High

1210546

HP1B3
Heterochromatin protein 1-binding protein 3

2

1

High-throughput

0.521

High

1247296

WDR74
WD repeat-containing protein 74

2

4

High-throughput

0.521

High

442503

GELS
Gelsolin

1

2

High-throughput

0.479

High

485481

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

2

High-throughput

0.479

High

551305

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.479

High

556387

CADH1
Cadherin-1

1

10

High-throughput

0.479

High

597904

FER
Tyrosine-protein kinase Fer

1

20

High-throughput

0.479

High

716640

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

7

High-throughput

0.479

High

724814

METK2
S-adenosylmethionine synthase isoform type-2

1

3

High-throughput

0.479

High

905225

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

911135

IMA1
Importin subunit alpha-1

1

3

High-throughput

0.479

High

996372

EF1A1
Elongation factor 1-alpha 1

1

5

High-throughput

0.479

High

1045857

TF65
Transcription factor p65

1

6

High-throughput

0.479

High

1114509

CUL3
Cullin-3

1

10

High-throughput

0.479

High

1143289

PLEC
Plectin

1

5

High-throughput

0.479

High

1153131

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

2

High-throughput

0.479

High

1411740

RIOK1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

1454231

ANFY1
Rabankyrin-5

1

11

High-throughput

0.479

High

1454234

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

1

High-throughput

0.479

High

941288

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

947299

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

530488

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

995317

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.445

High

1199954

P5CR3
Pyrroline-5-carboxylate reductase 3

1

2

High-throughput

0.445

High

373362

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.437

High

424466

HMGN1
Non-histone chromosomal protein HMG-14

1

3

High-throughput

0.437

High

481400

HMGB1
High mobility group protein B1

1

10

High-throughput

0.437

High

566860

PDIA4
Protein disulfide-isomerase A4

1

5

High-throughput

0.437

High

674357

BRD2
Bromodomain-containing protein 2

1

7

High-throughput

0.437

High

687312

HMGB2
High mobility group protein B2

1

10

High-throughput

0.437

High

1051879

EF1A2
Elongation factor 1-alpha 2

1

5

High-throughput

0.437

High

1255889

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1434929

CCD86
Coiled-coil domain-containing protein 86

1

2

High-throughput

0.437

High

1454165

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

2

High-throughput

0.437

High

1454235

SF3B6
Splicing factor 3B subunit 6

1

6

High-throughput

0.437

High

1450748

ASF1B
Histone chaperone ASF1B

1

0

High-throughput

0.426

High

239236

ZNRD2
Protein ZNRD2

1

4

High-throughput

0.407

High

1258601

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

10

High-throughput

0.407

High

1278584

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

3

High-throughput

0.407

High

1200287

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

2

0

High-throughput

0.298

High

1337428

SRFB1
Serum response factor-binding protein 1

2

0

High-throughput

0.298

High

1245429

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

0

High-throughput

0.249

Low

1271891

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

1416242

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.249

Low

1454233

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025