Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 22674379
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0043232 - intracellular non-membrane-bounded organelle
GO:0140693 - molecular condensate scaffold activity
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 414
Hs

1 440
+ Hs
+ Hs
+ Dr
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024