Protein: PURA
Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)

Gene: PURA
Organism: Mus musculus
Interactions: 37
UniProt ID: P42669

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000900 - mRNA regulatory element binding translation repressor activity
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

104475

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

0

High-throughput

0.602

High

840632

Q8BPK8
Fragile X messenger ribonucleoprotein 1

2

5

High-throughput

0.586

High

840625

NEB2
Neurabin-2

2

1

High-throughput

0.584

High

840623

FXR1
RNA-binding protein FXR1

1

5

High-throughput

0.536

High

840628

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.536

High

840630

MYOME
Myomegalin

1

1

High-throughput

0.536

High

840617

TNIK
Traf2 and NCK-interacting protein kinase

1

0

High-throughput

0.513

High

840635

TSC1
Hamartin

1

0

High-throughput

0.513

High

543015

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.501

High

666785

CCNB1
G2/mitotic-specific cyclin-B1

1

1

Small-scale

0.501

High

671882

CCND1
G1/S-specific cyclin-D1

1

2

Small-scale

0.501

High

718965

CDK4
Cyclin-dependent kinase 4

1

2

Small-scale

0.501

High

840610

H11
Histone H1.1

1

8

Small-scale

0.501

High

840613

CCNA2
Cyclin-A2

1

1

Small-scale

0.501

High

840620

CCNE1
G1/S-specific cyclin-E1

1

2

Small-scale

0.501

High

840634

DLGP1
Disks large-associated protein 1

1

1

High-throughput

0.489

High

542833

RARA
Retinoic acid receptor alpha

1

5

Small-scale

0.479

High

840611

CDK5
Cyclin-dependent kinase 5

1

1

Small-scale

0.479

High

840614

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

2

High-throughput

0.479

High

840618

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

3

High-throughput

0.479

High

840622

E2F1
Transcription factor E2F1

1

1

Small-scale

0.479

High

840624

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

10

High-throughput

0.479

High

840629

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.479

High

840633

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

840637

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

840638

MECP2
Methyl-CpG-binding protein 2

1

1

Small-scale

0.479

High

108507

G3X9H5
Huntingtin

1

0

High-throughput

0.458

High

840616

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

840627

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

840621

CCNH
Cyclin-H

1

3

Small-scale

0.457

High

777830

FMR1
Fragile X messenger ribonucleoprotein 1

1

5

High-throughput

0.445

High

840612

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.445

High

840615

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.445

High

840636

XPO7
Exportin-7

1

1

High-throughput

0.445

High

840626

TAOK2
Serine/threonine-protein kinase TAO2

1

1

High-throughput

0.437

High

840631

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

1

High-throughput

0.437

High

840619

SC6A4
Sodium-dependent serotonin transporter

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025