HitPredict

Interactor 1: PAK1 (Q13153)
Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)
Gene: PAK1

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 451
+	Hs
		1026217 PAK1_HUMAN (1-545): 0: 558: 100.00		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		933187 PAK1_HUMAN (1-545): 0: 558: 100.00		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		1026178 PAK1_HUMAN (1-545): 0: 558: 100.00		TBA3E_HUMAN (1-440): 0: 698: 97.05
+	Hs
		428176 PAK1_HUMAN (1-545): 0: 558: 100.00		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		933780 PAK1_HUMAN (1-545): 0: 558: 100.00		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		681913 AKT1_HUMAN (145-544): 8.19e-134: 399: 21.71		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		1023101 STK4_HUMAN (247-545): 2.66e-127: 382: 41.20		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		933421 STK4_HUMAN (247-545): 2.66e-127: 382: 41.20		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		428041 AKT1_HUMAN (145-544): 8.19e-134: 399: 21.71		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		681781 AKT1_HUMAN (145-544): 8.19e-134: 399: 21.71		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Ce
		110168 GCK1_CAEEL (239-539): 3.89e-122: 375: 43.05		O18688_CAEEL (1-439): 0: 700: 87.70
+	Hs
		933777 STK4_HUMAN (247-545): 2.66e-127: 382: 41.20		TBB4B_HUMAN (1-437): 0: 693: 40.50