HitPredict

Interactor 1: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1675 Hs			1 727
+	Hs
		318727 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RHBT1_HUMAN (1-708): 7.61e-161: 482: 67.65
+	Hs
		955066 CLH1_HUMAN (1-1675): 0: 3106: 100.00		CDC42_HUMAN (12-218): 7.12e-92: 286: 36.67
+	Hs
		601242 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RHOQ_HUMAN (10-225): 1.25e-84: 267: 36.53
+	Mm
		1229273 CLH1_MOUSE (1-1675): 0: 3105: 99.88		SPOP_MOUSE (305-670): 2.94e-72: 241: 13.30
+	Hs
		580994 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RAC2_HUMAN (12-219): 9.89e-73: 236: 36.97
+	Hs
		953396 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RAC3_HUMAN (12-208): 3.83e-72: 234: 39.50
+	Hs
		988284 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RAC1_HUMAN (12-220): 5.14e-72: 234: 35.38
+	Hs
		976209 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RB11A_HUMAN (5-252): 7.95e-71: 232: 16.34
+	Hs
		1015371 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RHOG_HUMAN (12-218): 7.1e-71: 231: 36.19
+	Hs
		1026056 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RB11B_HUMAN (5-252): 2.04e-70: 230: 15.54
+	Hs
		961958 CLH1_HUMAN (1-1675): 0: 3106: 100.00		RHOA_HUMAN (16-216): 1.77e-70: 230: 35.29
+	Dm
		715076 CLH_DROME (1-1663): 0: 2899: 80.17		RAC1_DROME (12-221): 1.02e-69: 228: 35.21