HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: PRD16 (Q9HAZ2)
Histone-lysine N-methyltransferase PRDM16 (EC 2.1.1.367) (PR domain zinc finger protein 16) (PR domain-containing protein 16) (Transcription factor MEL1) (MDS1/EVI1-like gene 1)
Gene: PRDM16

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30462309
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 1276
+	Hs
		64140 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN729_HUMAN (532-1275): 0: 597: 11.08
+	Hs
		974546 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		MECOM_HUMAN (1-1276): 2.56e-173: 548: 45.11
+	Hs
		983755 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF91_HUMAN (644-1276): 5.73e-168: 533: 10.52
+	Hs
		67424 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN850_HUMAN (6-608): 8.86e-159: 506: 16.53
+	Hs
		1027102 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN227_HUMAN (211-810): 4.38e-142: 453: 15.45
+	Hs
		1027126 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN615_HUMAN (31-470): 6.43e-121: 394: 20.40
+	Hs
		970657 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF45_HUMAN (433-948): 5.98e-118: 384: 8.49
+	Hs
		855966 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN132_HUMAN (2-417): 4.79e-107: 355: 17.91
+	Hs
		1027027 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN568_HUMAN (803-1199): 4.57e-98: 329: 16.28
+	Hs
		563302 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF16_HUMAN (947-1275): 5.28e-90: 308: 11.34
+	Hs
		728565 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF93_HUMAN (823-1200): 5.04e-88: 300: 16.54
+	Hs
		1027081 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN534_HUMAN (875-1200): 4.03e-74: 262: 15.99
+	Hs
		1027128 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN565_HUMAN (891-1098): 4.01e-63: 227: 24.04
+	Hs
		1027188 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN479_HUMAN (909-1098): 2.27e-57: 209: 26.32
+	Hs
		1027143 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN420_HUMAN (2-295): 8.51e-51: 194: 9.74
+	Hs
		1027150 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN480_HUMAN (781-1004): 1.42e-47: 181: 20.50
+	Hs
		599068 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF10_HUMAN (340-503): 2.44e-44: 172: 26.32
+	Hs
		1027024 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN829_HUMAN (177-333): 7.18e-32: 132: 22.84
+	Hs
		1027217 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN184_HUMAN (6-180): 3.23e-22: 105: 7.39
+	Hs
		1027123 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN283_HUMAN (1046-1201): 1.35e-11: 70.9: 8.70