HitPredict

Interactor 1: DNJC3 (Q13217)
DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)
Gene: DNAJC3

Interactor 2: SEC63 (Q9UGP8)
Translocation protein SEC63 homolog (DnaJ homolog subfamily C member 23)
Gene: SEC63

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~DnaJ
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 760
+	Hs
		1240182 TTC13_HUMAN (34-337): 1.83e-49: 183: 21.36		SEC63_HUMAN (1-742): 0: 750: 100.00
+	Hs
		1028112 DNJC3_HUMAN (1-504): 1.15e-88: 282: 100.00		DJB12_HUMAN (81-218): 1.24e-40: 155: 27.66
+	Sc
		541602 CYC8_YEAST (33-390): 1.82e-33: 137: 10.71		SEC63_YEAST (6-521): 5.25e-86: 287: 20.40
+	Hs
		1252944 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		DJB14_HUMAN (32-227): 6.7e-45: 167: 21.68
+	Hs
		1028127 DNJC3_HUMAN (1-504): 1.15e-88: 282: 100.00		DJC16_HUMAN (74-166): 3.35e-24: 110: 33.33
+	Hs
		1305100 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		DJC18_HUMAN (36-214): 2.82e-43: 162: 19.78
+	Hs
		1305121 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		DJB12_HUMAN (81-218): 1.24e-40: 155: 27.66
+	Hs
		279292 DNJC3_HUMAN (1-504): 1.15e-88: 282: 100.00		DNJB5_HUMAN (104-166): 5.53e-22: 100: 40.91
+	Hs
		1232197 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		ASCC3_HUMAN (602-735): 8.9e-37: 151: 24.65
+	Hs
		1245915 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		DNJB8_HUMAN (104-211): 4.17e-37: 140: 25.66
+	Hs
		1262557 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		DNJB3_HUMAN (104-209): 8.11e-38: 139: 27.03
+	Hs
		1305149 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		DJC16_HUMAN (74-166): 3.35e-24: 110: 33.33
+	Hs
		279337 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		DNJB5_HUMAN (104-166): 5.53e-22: 100: 40.91
+	Hs
		1252948 DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98		DJB14_HUMAN (32-227): 6.7e-45: 167: 21.68
+	Hs
		1245927 DNJB8_HUMAN (394-501): 4.62e-39: 143: 38.79		DJB12_HUMAN (81-218): 1.24e-40: 155: 27.66
+	Hs
		279350 DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13		DJB12_HUMAN (81-218): 1.24e-40: 155: 27.66
+	Hs
		636504 DNJB2_HUMAN (394-501): 1.3e-34: 134: 41.88		DNJB8_HUMAN (104-211): 4.17e-37: 140: 25.66
+	Hs
		272040 STIP1_HUMAN (24-460): 7.31e-16: 82: 10.91		U520_HUMAN (210-514): 2.95e-13: 76.1: 15.41