Protein: IASPP
RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)

Gene: IASPP, PPP1R13L
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q8WUF5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003215 - cardiac right ventricle morphogenesis
GO:0003229 - ventricular cardiac muscle tissue development
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

387184

P53
Cellular tumor antigen p53

10

14

Small-scale

0.971

High

978823

TF65
Transcription factor p65

2

10

Small-scale

0.821

High

1260084

IASPP
RelA-associated inhibitor

2

16

Small-scale

0.792

High

587647

NFKB1
Nuclear factor NF-kappa-B p105 subunit

2

20

Small-scale

0.789

High

961411

NFKB2
Nuclear factor NF-kappa-B p100 subunit

2

20

Small-scale

0.789

High

906042

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

10

20

Small-scale

0.759

High

919185

RAN
GTP-binding nuclear protein Ran

1

11

Small-scale

0.757

High

906543

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

7

20

Small-scale

0.752

High

1077044

MARE1
Microtubule-associated protein RP/EB family member 1

8

4

Small-scale

0.751

High

737941

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

6

20

Small-scale

0.732

High

1260090

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

18

High-throughput

0.698

High

225150

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

20

High-throughput

0.691

High

380820

S100B
Protein S100-B

1

2

High-throughput

0.691

High

789081

ABL2
Tyrosine-protein kinase ABL2

1

16

High-throughput

0.691

High

795830

MAGA4
Melanoma-associated antigen 4

3

11

High-throughput

0.667

High

175896

P73
Tumor protein p73

1

14

Small-scale

0.647

High

942831

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.647

High

1260093

P63
Tumor protein 63

1

14

Small-scale

0.647

High

1073931

PP1R7
Protein phosphatase 1 regulatory subunit 7

2

13

High-throughput

0.628

High

1049282

KEAP1
Kelch-like ECH-associated protein 1

2

4

Small-scale

0.624

High

1260095

TANC2
Protein TANC2

1

15

High-throughput

0.618

High

835470

GSK3A
Glycogen synthase kinase-3 alpha

1

13

High-throughput

0.618

High

835902

GSK3B
Glycogen synthase kinase-3 beta

1

14

High-throughput

0.618

High

1260088

AURKB
Aurora kinase B

1

4

High-throughput

0.618

High

1260096

ANLN
Anillin

1

3

High-throughput

0.618

High

998912

EP300
Histone acetyltransferase p300

2

15

Small-scale

0.611

High

1260089

WDR83
WD repeat domain-containing protein 83

3

7

High-throughput

0.609

High

1146662

A16L1
Autophagy-related protein 16-1

2

14

Small-scale

0.584

High

1190911

TAFA3
Chemokine-like protein TAFA-3

2

1

High-throughput

0.574

High

435143

SP1
Transcription factor Sp1

1

11

Small-scale

0.561

High

772080

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.561

High

1260104

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

Small-scale

0.561

High

1260094

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.553

High

158108

TX1B3
Tax1-binding protein 3

1

11

High-throughput

0.536

High

164984

SC16A
Protein transport protein Sec16A

1

6

High-throughput

0.536

High

210157

PRC1
Protein regulator of cytokinesis 1

1

5

High-throughput

0.536

High

245723

B4GT2
Beta-1,4-galactosyltransferase 2

1

1

High-throughput

0.536

High

316113

CBX6
Chromobox protein homolog 6

1

15

High-throughput

0.536

High

323924

BAG2
BAG family molecular chaperone regulator 2

1

7

High-throughput

0.536

High

402277

JUN
Transcription factor Jun

1

9

High-throughput

0.536

High

504464

HSP7C
Heat shock cognate 71 kDa protein

1

11

High-throughput

0.536

High

529472

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

796146

MAGA9
Melanoma-associated antigen 9

1

11

High-throughput

0.536

High

858114

NKX25
Homeobox protein Nkx-2.5

1

11

High-throughput

0.536

High

958735

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

2

High-throughput

0.536

High

1215902

I2BP1
Interferon regulatory factor 2-binding protein 1

1

1

High-throughput

0.536

High

1260098

GTSE1
G2 and S phase-expressed protein 1

1

1

High-throughput

0.536

High

1260103

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

2

High-throughput

0.536

High

1087837

PPR3A
Protein phosphatase 1 regulatory subunit 3A

2

2

Small-scale

0.533

High

856187

SPSY
Spermine synthase

1

0

High-throughput

0.513

High

882777

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

1128349

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1260097

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

1260108

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

1085615

HIF1A
Hypoxia-inducible factor 1-alpha

1

7

Small-scale

0.501

High

275071

RENR
Renin receptor

1

1

High-throughput

0.489

High

686711

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.489

High

1127656

PRC2B
Protein PRRC2B

1

20

High-throughput

0.489

High

1231189

KLH34
Kelch-like protein 34

1

6

High-throughput

0.489

High

1232936

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

4

High-throughput

0.489

High

1260099

HPBP1
Hsp70-binding protein 1

1

2

High-throughput

0.489

High

1260100

NHSL3
NHS-like protein 3

1

15

High-throughput

0.489

High

1260101

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

2

High-throughput

0.489

High

163051

XPO1
Exportin-1

1

10

High-throughput

0.479

High

308926

KI20A
Kinesin-like protein KIF20A

1

16

High-throughput

0.479

High

522093

CADH1
Cadherin-1

1

5

High-throughput

0.479

High

668850

PML
Protein PML

1

8

High-throughput

0.479

High

795778

MAGA3
Melanoma-associated antigen 3

1

11

Small-scale

0.479

High

818293

SOX2
Transcription factor SOX-2

1

9

High-throughput

0.479

High

1042137

CUL3
Cullin-3

1

16

High-throughput

0.479

High

1066446

KIF14
Kinesin-like protein KIF14

1

11

High-throughput

0.479

High

1081234

NF2L2
Nuclear factor erythroid 2-related factor 2

1

6

Small-scale

0.479

High

1081338

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

1120268

CEP55
Centrosomal protein of 55 kDa

1

3

Small-scale

0.479

High

1204740

CEP57
Centrosomal protein of 57 kDa

1

1

High-throughput

0.479

High

1260085

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

1260086

HDAC2
Histone deacetylase 2

1

9

High-throughput

0.479

High

1260087

CBP
CREB-binding protein

1

13

Small-scale

0.479

High

1260091

EGLN1
Egl nine homolog 1

1

6

Small-scale

0.479

High

1260092

ATG5
Autophagy protein 5

1

2

Small-scale

0.479

High

1260102

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1245100

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

834643

NU153
Nuclear pore complex protein Nup153

1

18

Small-scale

0.445

High

903833

NTF2
Nuclear transport factor 2

1

2

Small-scale

0.445

High

1260106

MARE3
Microtubule-associated protein RP/EB family member 3

1

4

Small-scale

0.437

High

62960

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.279

Low

562169

ANFB
Natriuretic peptides B

1

0

High-throughput

0.279

Low

1260107

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.279

Low

1260109

PCDGE
Protocadherin gamma-B2

1

0

High-throughput

0.279

Low

1260105

TMCO1
Calcium load-activated calcium channel

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024