Interactor 1: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 28977666, 29955894
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~PHD, PHD~PHD
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
and 6 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 835
Hs

1 1912
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024