Protein: CRLF2
Cytokine receptor-like factor 2 (Cytokine receptor-like 2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLP receptor)

Gene: CRLF2
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q9HC73

Gene Ontology (top 5):
GO:0004896 - cytokine receptor activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0009897 - external side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

333522

MPZL1
Myelin protein zero-like protein 1

1

3

High-throughput

0.691

High

898393

BCAM
Basal cell adhesion molecule

1

6

High-throughput

0.691

High

931998

EPHB4
Ephrin type-B receptor 4

1

10

High-throughput

0.691

High

1413587

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

6

High-throughput

0.691

High

161087

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

2

High-throughput

0.536

High

269706

PLXA2
Plexin-A2

1

9

High-throughput

0.536

High

343862

SEM4F
Semaphorin-4F

1

4

High-throughput

0.536

High

472130

MET
Hepatocyte growth factor receptor

1

17

High-throughput

0.536

High

541697

FGFR1
Fibroblast growth factor receptor 1

1

13

High-throughput

0.536

High

582199

INGR1
Interferon gamma receptor 1

1

3

High-throughput

0.536

High

641261

FGFR2
Fibroblast growth factor receptor 2

1

15

High-throughput

0.536

High

648685

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.536

High

650426

FGFR3
Fibroblast growth factor receptor 3

1

14

High-throughput

0.536

High

658776

JAK1
Tyrosine-protein kinase JAK1

1

20

High-throughput

0.536

High

690123

AVR2A
Activin receptor type-2A

1

5

High-throughput

0.536

High

787250

BMR1A
Bone morphogenetic protein receptor type-1A

1

5

High-throughput

0.536

High

787345

ACV1B
Activin receptor type-1B

1

5

High-throughput

0.536

High

876283

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

1

High-throughput

0.536

High

1111714

STIM1
Stromal interaction molecule 1

1

2

High-throughput

0.536

High

1309804

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

1

1

High-throughput

0.536

High

1323765

S39AB
Zinc transporter ZIP11

1

1

High-throughput

0.536

High

1348215

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.536

High

1435237

ANTR1
Anthrax toxin receptor 1

1

5

High-throughput

0.536

High

1438715

PDXL2
Podocalyxin-like protein 2

1

1

High-throughput

0.536

High

1438716

STIM2
Stromal interaction molecule 2

1

2

High-throughput

0.536

High

239500

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

1

0

High-throughput

0.513

High

300044

CBPD
Carboxypeptidase D

1

0

High-throughput

0.513

High

624677

SL9A1
Sodium/hydrogen exchanger 1

1

0

High-throughput

0.513

High

895372

S26A2
Sulfate transporter

1

0

High-throughput

0.513

High

935700

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.513

High

1217398

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

0

High-throughput

0.513

High

1350076

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

66300

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

1

High-throughput

0.489

High

885511

MA2A2
Alpha-mannosidase 2x

1

4

High-throughput

0.489

High

1008363

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

High-throughput

0.489

High

1206346

WDR44
WD repeat-containing protein 44

1

2

High-throughput

0.489

High

1248521

SUSD1
Sushi domain-containing protein 1

1

7

High-throughput

0.489

High

1281273

TMED4
Transmembrane emp24 domain-containing protein 4

1

1

High-throughput

0.489

High

1334569

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.489

High

1335219

NETO2
Neuropilin and tolloid-like protein 2

1

4

High-throughput

0.489

High

1336780

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

1

2

High-throughput

0.489

High

1357952

DCAKD
Dephospho-CoA kinase domain-containing protein

1

1

High-throughput

0.489

High

1382947

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.489

High

1414295

ABHEA
Protein ABHD14A

1

2

High-throughput

0.489

High

1438717

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

3

High-throughput

0.489

High

1438718

TM59L
Transmembrane protein 59-like

1

1

High-throughput

0.489

High

1162337

CEGT
Ceramide glucosyltransferase

1

0

High-throughput

0.279

Low

1204953

MTX3
Metaxin-3

1

0

High-throughput

0.279

Low

1214129

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

1307557

ZDH13
Palmitoyltransferase ZDHHC13

1

0

High-throughput

0.279

Low

1363587

PIGB
GPI alpha-1,2-mannosyltransferase 3

1

0

High-throughput

0.279

Low

1385116

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

1413904

LMF2
Lipase maturation factor 2

1

0

High-throughput

0.279

Low

1417392

TX13B
Testis-expressed protein 13B

1

0

High-throughput

0.279

Low

1418036

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

1429117

COA1
Cytochrome c oxidase assembly factor 1 homolog

1

0

High-throughput

0.279

Low

1438714

ARL8B
ADP-ribosylation factor-like protein 8B

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025