HitPredict

Interactor 1: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	zf-B_box~zf-B_box, zf-B_box~zf-C3HC4
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 835 Hs			1 783
+	Hs
		175691 TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1019296 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		TRI26_HUMAN (194-762): 5.09e-89: 292: 12.94
+	Hs
		1029844 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		TRIM6_HUMAN (195-774): 1.16e-86: 284: 12.69
+	Hs
		1030065 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		TRI17_HUMAN (195-768): 3.07e-78: 261: 13.38
+	Hs
		175623 TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78		TRI18_HUMAN (107-776): 5.63e-138: 424: 23.70
+	Hs
		175727 TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78		TRIM1_HUMAN (107-779): 9.11e-128: 400: 23.32
+	Hs
		1356047 TRIM1_HUMAN (40-589): 4.03e-64: 231: 15.36		TRIM1_HUMAN (107-779): 9.11e-128: 400: 23.32
+	Hs
		1029728 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		TRI11_HUMAN (1-121): 1.6e-09: 63.2: 20.66
+	Hs
		1029416 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		50877 TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78		FSD2_HUMAN (313-608): 9.33e-83: 281: 22.30
+	Mm
		1093410 LIN41_MOUSE (149-395): 1.87e-66: 239: 26.30		LIN41_MOUSE (123-744): 7.65e-79: 273: 15.22
+	Hs
		50986 TRIM1_HUMAN (40-589): 4.03e-64: 231: 15.36		FSD2_HUMAN (313-608): 9.33e-83: 281: 22.30
+	Dr
		91587 E7F1U3_DANRE (37-628): 1.73e-59: 218: 16.56		E7F1U3_DANRE (185-765): 3.19e-78: 269: 14.17
+	Hs
		1317480 TRIM1_HUMAN (40-589): 4.03e-64: 231: 15.36		TRI54_HUMAN (198-528): 4.04e-73: 244: 20.71
+	Hs
		1219924 TRIM1_HUMAN (40-589): 4.03e-64: 231: 15.36		TRI42_HUMAN (157-503): 1.27e-26: 118: 16.09
+	Hs
		175635 TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		537123 TRIM1_HUMAN (40-589): 4.03e-64: 231: 15.36		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		584879 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		RO52_HUMAN (120-378): 1.33e-12: 72.8: 10.81
+	Hs
		536737 PML_HUMAN (29-609): 1.21e-57: 214: 14.00		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77