Interactor 1: TOP2A (Q01320)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A
Interactor 2: AIRE (Q9Z0E3)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog)
Gene: AIRE
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 0.60 | 0.445 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20085707 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001673 - male germ cell nucleus GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025