HitPredict

Interactor 1: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Interactor 2: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 32302570, 12642610, 33495715
Identification Methods affinity chromatography technology, ultraviolet-visible spectroscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains NTF2~NTF2, RRM_1~RRM_1
Common GO terms GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
and 20 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 466
Hs

1 466
+ Hs
+ Hs
+ At
+ Hs
+ Dm
+ Sc
+ Hs
+ Mm
+ Dm
+ Dm
+ Hs
+ Rn
+ Sc
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024