Protein: SPK1
Serine/threonine-protein kinase spk-1 (EC 2.7.11.1)

Gene: SPK1, spk-1
Organism: Caenorhabditis elegans
Interactions: 49
UniProt ID: Q03563

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

873612

LIN2
Protein lin-2

2

10

High-throughput

0.743

High

976973

JAC1
Juxtamembrane domain-associated catenin

2

14

High-throughput

0.743

High

247932

PRY1
Axin-like protein pry-1

2

0

High-throughput

0.705

High

976956

HSP90
Heat shock protein 90

1

20

High-throughput

0.698

High

976971

RSP3
Probable splicing factor, arginine/serine-rich 3

1

20

Small-scale

0.647

High

136752

O01686
Oxysterol-binding protein

1

3

High-throughput

0.625

High

976954

PAR3
Partitioning defective protein 3

2

14

High-throughput

0.594

High

107413

BIR1
Chromosomal passenger complex protein bir-1

2

6

High-throughput

0.576

High

109637

H2KYX3
FERM domain-containing protein

2

18

High-throughput

0.576

High

219678

O44781
RNA helicase

2

20

High-throughput

0.576

High

712311

IF5A1
Eukaryotic translation initiation factor 5A-1

2

1

High-throughput

0.576

High

954498

P91457
RanBP2-type domain-containing protein

2

16

High-throughput

0.576

High

976957

SYFB
Phenylalanine--tRNA ligase beta subunit

2

1

High-throughput

0.576

High

976958

APC11
Anaphase-promoting complex subunit 11

2

2

High-throughput

0.576

High

976959

APR1
Adenomatous polyposis coli protein-related protein 1

2

2

High-throughput

0.576

High

976961

Q22137
1,4-alpha-glucan branching enzyme

2

2

High-throughput

0.576

High

976964

PSA2
Proteasome subunit alpha type-2

2

8

High-throughput

0.576

High

976969

Q95Y13
Nucleoporin Nup133/Nup155-like N-terminal domain-containing protein

2

1

High-throughput

0.576

High

976970

SEC13
Protein SEC13 homolog

2

20

High-throughput

0.576

High

105143

TACC1
Transforming acid coiled-coil-containing protein 1

2

0

High-throughput

0.551

High

976960

Q22078
Nuclear pore complex protein Nup85

2

0

High-throughput

0.551

High

220114

NH111
Nuclear hormone receptor family member nhr-111

1

20

High-throughput

0.541

High

856979

CLP1
Protein clpf-1

1

1

High-throughput

0.541

High

954344

P91306
CSD domain-containing protein

1

12

High-throughput

0.541

High

976953

ARF12
ADP-ribosylation factor 1-like 2

1

8

High-throughput

0.541

High

976955

Q17549
MAGUK p55 subfamily member 5

2

5

High-throughput

0.526

High

976963

Q22554
TPR_REGION domain-containing protein

1

0

High-throughput

0.518

High

976968

Q93156
BED-type domain-containing protein

1

10

High-throughput

0.508

High

185229

WASH1
WASH complex subunit homolog 1

1

4

High-throughput

0.494

High

976962

Q22174
Tr-type G domain-containing protein

1

11

High-throughput

0.494

High

976965

NU301
Nucleosome-remodeling factor subunit NURF301-like

1

18

High-throughput

0.494

High

88200

D3YT29
PDZ domain-containing protein

1

12

High-throughput

0.481

High

218219

HMP2
Beta-catenin-like protein hmp-2

1

15

High-throughput

0.481

High

248167

O62332
Importin N-terminal domain-containing protein

1

7

High-throughput

0.481

High

976952

GARS
Glycine--tRNA ligase

1

2

High-throughput

0.481

High

976972

Q9TXM1
Uncharacterized protein

1

3

High-throughput

0.479

High

86398

C1P633
PDZ domain-containing protein

1

14

High-throughput

0.457

High

110591

H2L2I2
Armadillo/beta-catenin-like repeat protein

1

15

High-throughput

0.457

High

248190

O62333
Importin N-terminal domain-containing protein

1

5

High-throughput

0.457

High

976966

Q8I711
Glycine--tRNA ligase

1

2

High-throughput

0.457

High

976974

Q9U3S8
BED-type domain-containing protein

1

6

High-throughput

0.457

High

107150

G5EES2
Moesin/ezrin/radixin homolog 1

1

17

High-throughput

0.439

High

976967

Q8ITW3
BZIP domain-containing protein

1

1

High-throughput

0.439

High

104023

G5EBK3
Moesin/ezrin/radixin homolog 1

1

17

High-throughput

0.417

High

110293

H2L0F6
BZIP domain-containing protein

1

1

High-throughput

0.417

High

103399

CDC26
Anaphase-promoting complex subunit CDC26

2

0

High-throughput

0.300

High

105427

G5ECR7
RNA polymerase II transcription factor SIII p18 subunit

2

0

High-throughput

0.300

High

712373

TPPC3
Trafficking protein particle complex subunit 3 homolog

2

0

High-throughput

0.300

High

220292

O45603
MEiosis-to-MItosis transition associated

1

0

High-throughput

0.282

High


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Last updated: 15 Jul 2024