Interactor 1: NC2B (Q01658)
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)
Gene: DR1
Interactor 2: DPOE3 (Q9NRF9)
DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17)
Gene: POLE3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.924 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 16189514, 32296183, 31515488, unassigned1304 |
| Identification Methods | two hybrid, two hybrid array, two hybrid prey pooling approach, mammalian protein protein interaction trap, validated two hybrid, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CBFD_NFYB_HMF~CBFD_NFYB_HMF |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity GO:0140672 - ATAC complex |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
