Protein: NC2B
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (dNC2)

Gene: NC2B, NC2beta
Organism: Drosophila melanogaster
Interactions: 29
UniProt ID: Q9VJQ5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001046 - core promoter sequence-specific DNA binding
GO:0005634 - nucleus
GO:0006338 - chromatin remodeling
GO:0016251 - RNA polymerase II general transcription initiation factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1465354

DPOE3
DNA polymerase epsilon subunit 3

3

10

Small-scale

0.847

High

1478663

Q9W2E3
Negative cofactor 2alpha

2

20

High-throughput

0.812

High

1469773

MOC2B
Molybdopterin synthase catalytic subunit

5

2

Small-scale

0.706

High

1478210

Q9VJ73
Ada2a-containing complex component 2

4

4

Small-scale

0.686

High

1427787

Q9GSP1
LD24434p

1

20

High-throughput

0.683

High

1269023

TAD2A
Transcriptional adapter 2A

4

5

Small-scale

0.672

High

1478662

DPOE4
DNA polymerase epsilon subunit 4

1

20

High-throughput

0.656

High

892383

TAF11
Transcription initiation factor TFIID subunit 11

3

3

High-throughput

0.653

High

1478656

Q9VLL1
D12

3

4

Small-scale

0.650

High

1463912

WDS
Protein will die slowly

2

2

Small-scale

0.584

High

569365

HAIR
Protein hairy

1

1

High-throughput

0.541

High

1374949

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

2

High-throughput

0.541

High

1478661

Q9W064
Dbx

1

3

High-throughput

0.541

High

613700

JRA
Transcription factor Jra

1

2

Small-scale

0.536

High

542919

DA
Protein daughterless

1

0

High-throughput

0.518

High

1014386

UBX
Homeotic protein ultrabithorax

1

5

High-throughput

0.481

High

1478665

X2JFG6
Uncharacterized protein, isoform C

1

1

High-throughput

0.481

High

1465789

HCF
Host cell factor

1

1

High-throughput

0.479

High

1474525

MBDR2
Protein MBD-R2

1

1

High-throughput

0.479

High

1478657

Q9VM59
Ada2a-containing complex component 1

1

2

High-throughput

0.479

High

1478658

Q9VTZ1
histone acetyltransferase

1

11

High-throughput

0.479

High

1478664

SGF29
SAGA-associated factor 29kDa

1

2

High-throughput

0.479

High

1478659

Q9VXC1
MIP06432p1

1

1

High-throughput

0.457

High

1269974

Q7KV89
Mitogen-activated protein kinase kinase kinase kinase

1

3

Small-scale

0.437

High

1269956

Q7KV88
Mitogen-activated protein kinase kinase kinase kinase

1

3

Small-scale

0.407

High

1343654

Q8SX89
Kugelkern, isoform A

1

0

High-throughput

0.265

Low

1471656

Q9VDK2
GH15831p

1

0

High-throughput

0.265

Low

1478660

PGPLE
Peptidoglycan-recognition protein LE

1

0

High-throughput

0.249

Low

305083

BM02
Bomanin Short 2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025