Protein: NCB2
Negative cofactor 2 complex subunit beta (NC2 complex subunit beta) (Transcriptional repressor YDR1)

Gene: NCB2
Organism: Saccharomyces cerevisiae S288C
Interactions: 18
UniProt ID: Q92317

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001046 - core promoter sequence-specific DNA binding
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

818601

NCB1
Negative cofactor 2 complex subunit alpha

9

20

Small-scale

0.968

High

561556

TBP
TATA-box-binding protein

5

4

Small-scale

0.912

High

734507

BTAF1
TATA-binding protein-associated factor MOT1

4

6

Small-scale

0.672

High

1362956

NCB2
Negative cofactor 2 complex subunit beta

1

11

High-throughput

0.656

High

381332

H2B1
Histone H2B.1

1

5

High-throughput

0.575

High

864446

IKS1
Probable serine/threonine-protein kinase IKS1

1

1

High-throughput

0.501

High

745513

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

Small-scale

0.480

High

382438

H4
Histone H4

1

3

High-throughput

0.479

High

708665

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

708811

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.479

High

1085017

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.479

High

647260

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

1054887

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

742787

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

1035362

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

8

High-throughput

0.445

High

700189

POP5
Ribonuclease P/MRP protein subunit POP5

1

0

High-throughput

0.249

Low

639099

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025