Interactor 1: PLD1 (Q13393)
Phospholipase D1 (PLD 1) (hPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1)
Gene: PLD1

Interactor 2: RHEB (Q15382)
GTP-binding protein Rheb (Ras homolog enriched in brain) (EC 3.6.5.-)
Gene: RHEB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.747

The method score is based on:

Property Details
Experiments 18550814
Identification Methods pull down, affinity chromatography technology, enzymatic study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Ras
Common GO terms GO:0000139 - Golgi membrane
GO:0005765 - lysosomal membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0007264 - small GTPase-mediated signal transduction
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1074
Hs

1 184
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024