HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: TFG (Q92734)
Protein TFG (TRK-fused gene protein)
Gene: TFG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	25416956, 24999758
Identification Methods	two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 400
+	Hs
		124632 EYA2_HUMAN (27-278): 1.49e-18: 91.3: 20.16		TFG_HUMAN (1-400): 1.73e-78: 249: 100.00
+	Hs
		130564 RBP56_HUMAN (109-555): 5.81e-53: 193: 35.05		SPT5H_HUMAN (88-278): 2.25e-09: 61.5: 12.31
+	Hs
		1033338 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		PCLO_HUMAN (106-310): 6.47e-13: 73: 16.59
+	Hs
		925711 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		SC24C_HUMAN (97-340): 4.13e-09: 60.7: 14.69
+	Hs
		319093 EWS_HUMAN (1-656): 1.53e-47: 179: 100.00		SC24D_HUMAN (161-366): 7.94e-09: 59.6: 15.94
+	Hs
		130343 EYA4_HUMAN (3-271): 6.1e-39: 154: 18.02		SPT5H_HUMAN (88-278): 2.25e-09: 61.5: 12.31
+	Hs
		130390 FUS_HUMAN (55-545): 1.16e-31: 131: 30.35		SPT5H_HUMAN (88-278): 2.25e-09: 61.5: 12.31
+	Hs
		130313 HTSF1_HUMAN (310-448): 3.37e-28: 122: 20.55		SPT5H_HUMAN (88-278): 2.25e-09: 61.5: 12.31