HitPredict

Interactor 1: PPR3D (O95685)
Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1 regulatory subunit 6) (PP1 subunit R6) (Protein phosphatase 1-binding subunit R6)
Gene: PPP1R3D

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.739

The method score is based on:

Property Details
Experiments 26186194, 27880917, 28514442, 28330616, 33961781, 22321011
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004722 - protein serine/threonine phosphatase activity
GO:0005977 - glycogen metabolic process
GO:0005979 - regulation of glycogen biosynthetic process
GO:0005981 - regulation of glycogen catabolic process
GO:0008157 - protein phosphatase 1 binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 299
Hs

1 330
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024