HitPredict

Interactor 1: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26725010, 29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 582
+	Hs
		1083268 RBBP7_HUMAN (429-613): 3.4e-25: 110: 17.41		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Dm
		1279315 EBI_DROME (361-623): 1.18e-46: 177: 16.67		LAR4_DROME (7-205): 4e-47: 180: 22.39
+	Hs
		403149 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		903196 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516438 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Ce
		953960 LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50		Q19581_CAEEL (101-477): 1.67e-48: 179: 12.27
+	Hs
		1316912 NLE1_HUMAN (466-625): 5.77e-36: 143: 14.55		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		1346955 NLE1_HUMAN (466-625): 5.77e-36: 143: 14.55		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Ce
		953961 LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50		EIF3G_CAEEL (62-188): 2.53e-25: 107: 31.50
+	Hs
		1077517 NLE1_HUMAN (466-625): 5.77e-36: 143: 14.55		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		903314 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23