Interactor 1: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Interactor 2: CRBN (Q96SW2)
Protein cereblon
Gene: CRBN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 27338790, 30458989, 33470442, 34978798, 24292623, 26990986, 27329811, 24292625, 30385546, 30760870, 33288957, 32391793, 24328678, 26183205
Identification Methods pull down, affinity chromatography technology, enzymatic study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LON_substr_bdg~zf-C2H2, Yippee-Mis18~zf-C2H2
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0046872 - metal ion binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 519
Hs

1 442
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024