Protein: WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2)

Gene: WWP2
Organism: Mus musculus
Interactions: 14
UniProt ID: Q9DBH0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004842 - ubiquitin-protein transferase activity
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

996054

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

20

Small-scale

0.647

High

1021794

SMRC1
SWI/SNF complex subunit SMARCC1

2

11

Small-scale

0.639

High

476248

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

9

Small-scale

0.578

High

1037930

GSC
Homeobox protein goosecoid

1

2

Small-scale

0.578

High

629457

PO5F1
POU domain, class 5, transcription factor 1

1

4

Small-scale

0.501

High

147889

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

12

Small-scale

0.479

High

466755

EGR2
E3 SUMO-protein ligase EGR2

1

4

Small-scale

0.479

High

873051

SOX2
Transcription factor SOX-2

1

9

Small-scale

0.479

High

1000419

IRF7
Interferon regulatory factor 7

1

2

Small-scale

0.479

High

1064948

RUNX2
Runt-related transcription factor 2

1

11

Small-scale

0.479

High

1298188

DIDO1
Death-inducer obliterator 1

1

13

Small-scale

0.479

High

1362900

Q921K2
Poly [ADP-ribose] polymerase

1

7

Small-scale

0.479

High

1282024

TCAM1
TIR domain-containing adapter molecule 1

1

12

Small-scale

0.437

High

1296512

WBP1L
WW domain binding protein 1-like

1

10

Small-scale

0.437

High


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Last updated: 11Aug2025