HitPredict

Interactor 1: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Interactor 2: RHPN1 (Q8TCX5)
Rhophilin-1 (GTP-Rho-binding protein 1)
Gene: RHPN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 540 Hs			1 670
+	Hs
		1033920 SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00		LIN7B_HUMAN (457-627): 3.12e-37: 140: 21.29
+	Hs
		1033929 SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00		LIN7C_HUMAN (452-617): 1.43e-35: 135: 21.32
+	Hs
		158280 SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00		LIN7A_HUMAN (457-615): 6.95e-35: 134: 20.00
+	Hs
		663961 PTN4_HUMAN (5-331): 4.46e-37: 148: 15.43		PTN4_HUMAN (211-629): 1.77e-39: 158: 12.17
+	Hs
		1334777 LIN7B_HUMAN (25-229): 4.57e-39: 143: 28.23		LIN7C_HUMAN (452-617): 1.43e-35: 135: 21.32
+	Mm
		1206509 GOPC_MOUSE (92-199): 2.77e-34: 136: 39.82		GOPC_MOUSE (289-666): 3.31e-35: 140: 15.29
+	Hs
		1336600 GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82		GOPC_HUMAN (289-623): 4.04e-32: 131: 15.88
+	Mm
		292491 DLG1_MOUSE (7-322): 5.28e-28: 120: 17.13		LIN7C_MOUSE (452-617): 1.43e-35: 135: 21.32
+	Rn
		677810 LIN7B_RAT (25-229): 5.17e-39: 143: 27.75		DLG4_RAT (460-595): 1.6e-18: 91.9: 19.86
+	Hs
		942382 LIN7B_HUMAN (25-229): 4.57e-39: 143: 28.23		DLG4_HUMAN (460-595): 1.79e-18: 91.9: 19.86
+	Hs
		158271 LIN7A_HUMAN (82-202): 4.94e-35: 133: 32.23		DLG4_HUMAN (460-595): 1.79e-18: 91.9: 19.86
+	Hs
		942387 LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75		DLG4_HUMAN (460-595): 1.79e-18: 91.9: 19.86
+	Mm
		1113136 Q3UP61_MOUSE (7-322): 8.27e-29: 123: 17.13		DLG4_MOUSE (460-595): 1.7e-18: 91.9: 19.86
+	Mm
		1143467 DLG2_MOUSE (4-336): 1.3e-28: 122: 13.08		DLG4_MOUSE (460-595): 1.7e-18: 91.9: 19.86
+	Mm
		1143387 DLG1_MOUSE (7-322): 5.28e-28: 120: 17.13		DLG4_MOUSE (460-595): 1.7e-18: 91.9: 19.86
+	Hs
		1246435 LIN7B_HUMAN (25-229): 4.57e-39: 143: 28.23		INADL_HUMAN (360-666): 4.51e-11: 68.4: 10.31
+	Mm
		936188 DLG2_MOUSE (4-336): 1.3e-28: 122: 13.08		DLG3_MOUSE (419-592): 3.45e-16: 84.6: 16.85
+	Hs
		1246444 LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75		INADL_HUMAN (360-666): 4.51e-11: 68.4: 10.31
+	Hs
		158295 LIN7A_HUMAN (82-202): 4.94e-35: 133: 32.23		INADL_HUMAN (360-666): 4.51e-11: 68.4: 10.31