HitPredict

Interactor 1: PRS8 (P41836)
26S proteasome regulatory subunit 8 homolog (Protein let1)
Gene: let1

Interactor 2: RPN11 (P41878)
26S proteasome regulatory subunit rpn11 (Protein pad1)
Gene: RPN11

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20838651
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~Prot_ATP_ID_OB_C
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 403 Sp			1 308
+	Sp
		267648 PRS10_SCHPO (21-401): 8.96e-155: 443: 45.29		RPN11_SCHPO (1-308): 4.22e-107: 316: 100.00
+	Dm
		874995 PRS4_DROME (7-395): 3.14e-134: 393: 44.22		PSDE_DROME (1-308): 7.54e-111: 325: 67.86
+	At
		1442984 PRS4A_ARATH (7-393): 1.79e-133: 391: 45.22		PSDE_ARATH (1-308): 1.67e-110: 324: 69.81
+	Hs
		138051 PRS4_HUMAN (9-395): 2.69e-134: 393: 45.48		PSDE_HUMAN (19-308): 2.24e-105: 311: 70.35
+	Dm
		1463624 Q9V405_DROME (1-399): 1.28e-122: 362: 40.60		PSDE_DROME (1-308): 7.54e-111: 325: 67.86
+	Hs
		138052 PRS8_HUMAN (3-403): 1.15e-125: 370: 78.30		PSDE_HUMAN (19-308): 2.24e-105: 311: 70.35
+	Hs
		138008 PRS6B_HUMAN (10-399): 5.59e-124: 366: 41.80		PSDE_HUMAN (19-308): 2.24e-105: 311: 70.35
+	Dm
		1267697 Q7KMQ0_DROME (80-388): 3.54e-111: 334: 55.34		PSDE_DROME (1-308): 7.54e-111: 325: 67.86
+	Hs
		137990 PRS7_HUMAN (80-388): 2.38e-112: 337: 56.31		PSDE_HUMAN (19-308): 2.24e-105: 311: 70.35
+	Hs
		969011 PRS8_HUMAN (3-403): 1.15e-125: 370: 78.30		CSN5_HUMAN (28-304): 3.46e-73: 230: 30.10
+	Dm
		684544 PRS4_DROME (7-395): 3.14e-134: 393: 44.22		PSMD7_DROME (26-307): 6.47e-60: 196: 19.05
+	Hs
		906494 PRS4_HUMAN (9-395): 2.69e-134: 393: 45.48		PSMD7_HUMAN (27-307): 4.25e-59: 193: 19.80
+	At
		1422014 PRS4A_ARATH (7-393): 1.79e-133: 391: 45.22		PSD7B_ARATH (15-307): 3.71e-57: 188: 18.09
+	At
		200895 PRS4A_ARATH (7-393): 1.79e-133: 391: 45.22		PSD7A_ARATH (15-307): 4.7e-57: 188: 17.76
+	Hs
		778747 PRS7_HUMAN (80-388): 2.38e-112: 337: 56.31		CSN5_HUMAN (28-304): 3.46e-73: 230: 30.10
+	Hs
		906495 PRS8_HUMAN (3-403): 1.15e-125: 370: 78.30		PSMD7_HUMAN (27-307): 4.25e-59: 193: 19.80
+	Hs
		851269 PRS6B_HUMAN (10-399): 5.59e-124: 366: 41.80		PSMD7_HUMAN (27-307): 4.25e-59: 193: 19.80
+	Dm
		684560 Q9V405_DROME (1-399): 1.28e-122: 362: 40.60		PSMD7_DROME (26-307): 6.47e-60: 196: 19.05
+	Dm
		684551 Q7KMQ0_DROME (80-388): 3.54e-111: 334: 55.34		PSMD7_DROME (26-307): 6.47e-60: 196: 19.05
+	Hs
		778636 PRS7_HUMAN (80-388): 2.38e-112: 337: 56.31		PSMD7_HUMAN (27-307): 4.25e-59: 193: 19.80