HitPredict

Interactor 1: SF3B2 (Q13435)
Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (Spliceosome-associated protein 145) (SAP 145)
Gene: SF3B2

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

The method score is based on:

Property	Details
Experiments	28515276, 22365833
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing and 4 others more... GO:0008380 - RNA splicing GO:0016607 - nuclear speck GO:0071005 - U2-type precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	895
Hs

1	2335

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024