HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: RPAP3 (Q9H6T3)
RNA polymerase II-associated protein 3
Gene: RPAP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_1~TPR_1, TPR_1~TPR_16, TPR_1~TPR_8, TPR_1~TPR_6, TPR_16~TPR_6
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 457 Hs			1 665
+	Hs
		174855 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		174814 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		684691 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		297056 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		TOM70_HUMAN (36-379): 1.61e-15: 82.2: 16.52
+	Hs
		858619 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		PPP5_HUMAN (131-251): 3.46e-14: 77.4: 32.23
+	Hs
		684646 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		1053193 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		RPAP3_HUMAN (1-665): 1.27e-121: 378: 100.00
+	Hs
		685029 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		RPAP3_HUMAN (1-665): 1.27e-121: 378: 100.00
+	Hs
		118697 AIP_HUMAN (144-414): 1.52e-49: 173: 16.72		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		174884 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Hs
		174661 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		OGT1_HUMAN (202-656): 7.67e-29: 125: 11.89
+	Dm
		817472 FKB12_DROME (153-247): 2.5e-20: 87.6: 26.26		Q9VPN5_DROME (2-272): 3.38e-31: 129: 21.82
+	Hs
		684718 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		1012412 Q0VDC6_HUMAN (151-247): 5.97e-21: 90.6: 26.73		TMTC1_HUMAN (260-662): 3.04e-26: 116: 12.75
+	Hs
		684432 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		645855 FKBP2_HUMAN (153-255): 1.29e-23: 98: 27.52		TTC13_HUMAN (13-256): 2.3e-19: 94.7: 10.53
+	Hs
		684975 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		DNJC7_HUMAN (42-289): 2.69e-15: 81.2: 16.11
+	Hs
		684549 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		PPP5_HUMAN (131-251): 3.46e-14: 77.4: 32.23
+	Hs
		213490 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		SGTA_HUMAN (232-399): 1.71e-12: 70.9: 33.33
+	Hs
		684824 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		CTR9_HUMAN (203-663): 7.24e-09: 61.2: 9.07