HitPredict

Interactor 1: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Interactor 2: PDIA6 (Q15084)
Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7)
Gene: PDIA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30948266
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 440
+	Hs
		1035895 BIRC3_HUMAN (1-604): 0: 676: 100.00		TXND5_HUMAN (177-431): 3.21e-41: 153: 20.37
+	Hs
		531818 BIRC3_HUMAN (1-604): 0: 676: 100.00		PDIA4_HUMAN (67-271): 1.28e-17: 87.3: 22.28
+	Hs
		423220 BIRC3_HUMAN (1-604): 0: 676: 100.00		PDIA1_HUMAN (62-387): 6.18e-10: 63: 11.59
+	Hs
		671807 BIRC3_HUMAN (1-604): 0: 676: 100.00		PDIA3_HUMAN (13-386): 9.31e-10: 62.6: 11.02
+	Hs
		1036270 BIRC2_HUMAN (2-604): 0: 643: 72.31		PDIA5_HUMAN (153-431): 3.2e-11: 67.2: 13.01
+	Dm
		1097121 DIAP2_DROME (9-100): 4.66e-25: 110: 31.52		PDIA6_DROME (1-423): 1.46e-112: 339: 56.91