HitPredict

Interactor 1: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Interactor 2: UBP35 (Q9P2H5)
Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.4.19.12) (Deubiquitinating enzyme 35) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35)
Gene: USP35

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35022505
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 1018
+	Hs
		177729 BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00		UBP35_HUMAN (1-1018): 0: 1039: 100.00
+	Hs
		177700 BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00		UBP38_HUMAN (1-993): 0: 884: 38.73
+	Hs
		1035953 BIRC3_HUMAN (1-604): 0: 676: 100.00		UBP7_HUMAN (750-997): 9.61e-30: 129: 22.22
+	Hs
		1036312 BIRC2_HUMAN (2-604): 0: 643: 72.31		UBP7_HUMAN (750-997): 9.61e-30: 129: 22.22
+	Hs
		1264879 RFFL_HUMAN (254-604): 6.11e-54: 189: 15.88		UBP28_HUMAN (332-984): 7.5e-73: 264: 17.42
+	Hs
		800606 RFFL_HUMAN (254-604): 6.11e-54: 189: 15.88		UBP5_HUMAN (237-926): 1.54e-70: 254: 13.39
+	Hs
		957751 XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21		UBP7_HUMAN (750-997): 9.61e-30: 129: 22.22
+	Hs
		957762 XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21		UBP47_HUMAN (686-983): 1.78e-26: 119: 17.86
+	Hs
		1264871 RFFL_HUMAN (254-604): 6.11e-54: 189: 15.88		UBP7_HUMAN (750-997): 9.61e-30: 129: 22.22
+	Hs
		777082 BIRC6_HUMAN (7-136): 3.42e-35: 144: 20.29		UBP8_HUMAN (660-932): 4.52e-38: 156: 21.22
+	Hs
		271165 BIRC7_HUMAN (13-165): 1.87e-34: 134: 21.80		UBP2_HUMAN (660-930): 5.02e-41: 162: 18.91
+	Dm
		1097052 DIAP1_DROME (20-173): 1.43e-24: 108: 24.36		Q7JQI1_DROME (601-999): 1.53e-45: 179: 21.78
+	Dm
		1176741 Q9VEM2_DROME (253-324): 1.46e-20: 90.5: 32.47		Q7JQI1_DROME (601-999): 1.53e-45: 179: 21.78
+	Hs
		271156 MYLIP_HUMAN (479-603): 3.16e-23: 104: 25.60		UBP2_HUMAN (660-930): 5.02e-41: 162: 18.91
+	Hs
		177733 BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00		UBP22_HUMAN (622-926): 7.16e-41: 160: 15.12
+	Zm
		8843 A0A1D6L1J9_MAIZE (529-602): 2.55e-20: 96.2: 28.38		A0A1D6ESQ1_MAIZE (777-925): 8.59e-17: 87.9: 25.81