HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Interactor 2: RBM45 (Q8IUH3)
RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45)
Gene: RBM45

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25939382
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0030154 - cell differentiation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 476
+	Hs
		1031313 SQSTM_HUMAN (1-440): 0: 760: 100.00		PABP4_HUMAN (5-411): 7.51e-60: 209: 14.73
+	Hs
		516499 SQSTM_HUMAN (1-440): 0: 760: 100.00		PABP1_HUMAN (382-470): 6.62e-13: 72.7: 11.58
+	Mm
		936679 SQSTM_MOUSE (1-440): 0: 731: 90.72		ELAV1_MOUSE (5-108): 7.3e-12: 68.2: 24.04
+	Hs
		319819 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		PABP4_HUMAN (5-411): 7.51e-60: 209: 14.73
+	Dr
		94548 MIB1_DANRE (105-233): 1.14e-42: 162: 24.43		PABPA_DANRE (382-470): 1.22e-12: 71.9: 11.58
+	Hs
		319701 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		PABP1_HUMAN (382-470): 6.62e-13: 72.7: 11.58
+	Hs
		320052 HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50		PUF60_HUMAN (38-180): 7.95e-12: 69.3: 28.28