Interactor 1: TDG (Q13569)
G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.29) (Thymine-DNA glycosylase) (hTDG)
Gene: TDG

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.735

The method score is based on:

Property Details
Experiments 24532795, 24394593, 11864601, 17060459, 24748645, 28680062
Identification Methods affinity chromatography technology, pull down, two hybrid, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0140297 - DNA-binding transcription factor binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 410
Hs

1 2442
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024